Evidence map›Paper›PMID 26625506›Full record

Trial reportThe American journal of managed care2015

A randomized controlled trial of negative co-payments: the CHORD trial.

Kevin G Volpp, Andrea B Troxel, Judith A Long, Said A Ibrahim, Dina Appleby, J Otis Smith, Jane Jaskowiak, Marie Helweg-Larsen, Jalpa A Doshi, Stephen E Kimmel

Open access · greenAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in The American journal of managed care, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. How to make value-based health insurance designs more effective? A systematic review and meta-analysis.The European journal of health economics : HEPAC : health economics in prevention and care · 2019
    Pooled it
  4. Trial
  5. Article
  6. Study design of BETTER-BP: Behavioral economics trial to enhance regulation of blood pressure.International journal of cardiology. Cardiovascular risk and prevention · 2022
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Kevin G VolppCenter for Health Equity Research & Promotion, Philadelphia Veterans Affairs Medical Center, PA
Andrea B Troxel
Judith A Long
Said A Ibrahim
Dina Appleby
J Otis Smith
Jane Jaskowiak
Marie Helweg-Larsen
Jalpa A Doshi
Stephen E Kimmel
Veterans Health Administration · US

Funding

The Penn Roybal Center on Behavioral Economics and Health: Solving for Scale and Impact with Design Thinking, Digital Platforms, and Dynamic AdaptationP30AG034546 · NIA · UNIVERSITY OF PENNSYLVANIA · PI Alison Meredith Buttenheim, KEVIN G VOLPP · 2009 to 2026
$10.6M
NIA NIH HHS P30 AG034546
6 · The paper itself

Abstract

objectivesValue-based insurance designs are being widely used. We undertook this study to examine whether a financial incentive that lowered co-payments for blood pressure medications below $0 improved blood pressure control among patients with poorly controlled hypertension. STUDY

designRandomized controlled trial.

methodsParticipants from 3 Pennsylvania hospitals (n = 337) were randomly assigned to: a) be paid $8 per medication per month for filling blood pressure prescriptions, b) a computerized behavioral intervention (CBI), c) both payment and CBI, or d) usual care. The primary outcome was change in blood pressure between baseline and 12 months post enrollment. We also measured adherence using the medication possession ratio in a subset of participants.

resultsThere were no significant interactions between the incentive and the CBI interventions. There were no significant changes in medication possession ratio in the treatment group. Blood pressure decreased among all participants, but to a similar degree between the financial incentive and control groups. Systolic blood pressure (SBP) dropped 13.7 mm Hg for the incentive group versus 10.0 mm Hg for the control group (difference = –3.7; 95% CI, –9.0 to 1.6; P = .17). The proportion of patients with blood pressure under control 12 months post enrollment was 35.6% of the incentive group versus 27.7% of the control group (odds ratio, 1.4; 95% CI, 0.8-2.5; P = .19). Diabetics in the incentive group had an average drop in SBP of 12.7 mm Hg between baseline and 12 months compared with 4.0 mm Hg in the control group (P = .02). Patients in the incentive group without diabetes experienced average SBP reductions of 15.0 mm Hg, compared with 16.3 mm Hg for control group nondiabetics (P = .71).

conclusionsAmong patients with poorly controlled blood pressure, financial incentives—as implemented in this trial—did not improve blood pressure control or adherence except among patients with diabetes.

Indexed as

Deductibles and CoinsuranceMedication AdherenceAntihypertensive AgentsFemaleHumansHypertensionMaleMiddle AgedPennsylvaniaAntihypertensive Agents

Identifiers

PMID26625506
PMCPMC6171502
OpenAlexW2411196887

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.