ArticleJournal of the Pediatric Infectious Diseases Society2014
Role of Human Bocavirus in Upper Respiratory Tract Infections and Acute Otitis Media.
Article in Journal of the Pediatric Infectious Diseases Society, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 33 citations in OpenAlex.
- The Role of Quantitative PCR in Evaluating the Clinical Significance of Human Bocavirus Detection in Children.Viruses · 2024Article
- Air pollutants, seasonal influenza, and acute otitis media in children: a population-based analysis using 22-year hospitalization data.BMC public health · 2024Article
- Case-control study of relationship of infection by respiratory viruses with acute otitis media in Chinese children.Heliyon · 2023Article
- Comparison of MT-PCR with Quantitative PCR for Human Bocavirus in Respiratory Samples with Multiple Respiratory Viruses Detection.Diagnostics (Basel, Switzerland) · 2023Article
- Human bocavirus-1 infections in Australian children aged < 2 years: a birth cohort study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2023Article
- HBoV-1: virus structure, genomic features, life cycle, pathogenesis, epidemiology, diagnosis and clinical manifestations.Frontiers in cellular and infection microbiology · 2023Review
- Human Bocavirus infection among children with respiratory tract infection in Ibadan, Nigeria.Access microbiology · 2022Article
- Effectiveness and safety of Danmu extract syrup for acute upper respiratory tract infection in children: A real-world, prospective cohort study.Journal of evidence-based medicine · 2022Article
- Article
- Detection of Respiratory Viruses from ARTI Patients by xTAG RVP Fast v2 Assay and Conventional Methods.The Malaysian journal of medical sciences : MJMS · 2017Article
- Human Bocavirus Capsid Messenger RNA Detection in Children With Pneumonia.The Journal of infectious diseases · 2017Article
- Panel 4: Report of the Microbiology Panel.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2017Review
- Clinical Evaluation of the New High-Throughput Luminex NxTAG Respiratory Pathogen Panel Assay for Multiplex Respiratory Pathogen Detection.Journal of clinical microbiology · 2016Article
- Determining Persistence of Bocavirus DNA in the Respiratory Tract of Children by Pyrosequencing.The Pediatric infectious disease journal · 2016Article
- Indictment by Association: Once Is Not Enough.The Journal of infectious diseases · 2015Article
- Importance of viruses in acute otitis media.Current opinion in pediatrics · 2015Review
- Symptomatic and asymptomatic respiratory viral infections in the first year of life: association with acute otitis media development.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2015Article
- Acute bacterial sinusitis complicating viral upper respiratory tract infection in young children.The Pediatric infectious disease journal · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
backgroundHuman bocavirus (HBoV) is a newly described parvovirus. HBoV1 has been associated with respiratory infections, including acute otitis media (AOM), but the knowledge on the significance of HBoV1 in upper respiratory tract infections (URI) and AOM in relation to other respiratory viruses is limited. The objective of this study was to compare the rate of detection of HBoV1 to that of other respiratory viruses in specimens from children with URI, with and without AOM complication.
methodsNasopharyngeal secretions (NPS) were collected during URI from healthy children (6-35 months) followed prospectively for 1 year; specimens have been previously analyzed for broad spectrum of respiratory viruses. Archived NPS were analyzed for HBoV1 using a high-throughput, quantitative polymerase chain reaction method.
resultsSeven hundred and seven NPS samples collected during URI episodes from 201 children were studied for HBoV1. A total of 94 (47%) children tested positive for HBoV1 DNA during 172 (24%) URI episodes; HBoV1 was present as the only virus in 44 (6%) URI episodes. Overall, 37% of URI episodes were complicated by AOM. Of URI associated with single virus (n = 303), the rate of AOM complicating URI associated with HBoV1 only was 52% (23 of 44); this was a higher AOM rate, compared to that of other respiratory viruses.
conclusionsAmong URI associated with single respiratory virus, HBoV1-URI was commonly associated with AOM complication. The important role of HBoV1 on AOM pathogenesis needs to be studied further.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.