ArticlePloS one2015
Factors Affecting Gender Differences in the Association between Health-Related Quality of Life and Metabolic Syndrome Components: Tehran Lipid and Glucose Study.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Metabolic syndrome and quality of life: a systematic review.Revista latino-americana de enfermagem · 2016Pooled it
- Relative handgrip strength mediates the association between metabolic syndrome and health-related quality of life among Korean adult women.BMC research notes · 2026Article
- Health-related quality of life among injured farmers in rural Vietnam: an analysis using EQ-5D-5 L.Scientific reports · 2026Article
- Health-related quality of life in adults with metabolic syndrome: a multi-level analysis of family and individual level variation.BMJ open · 2024Article
- Role of gender in explaining metabolic syndrome risk factors in an Iranian rural population using structural equation modelling.Scientific reports · 2023Article
- Patterns of metabolic syndrome and associated factors in women from the ELSA-Brasil: a latent class analysis approach.Cadernos de saude publica · 2023Article
- Relationship between quality of life and adolescent glycolipid metabolism disorder: A cohort study.World journal of diabetes · 2022Article
- The association of quality of life and personality characteristics with adolescent metabolic syndrome: a cohort study.Health and quality of life outcomes · 2021Article
- Abdominal obesity and hypertension are correlated with health-related quality of life in Taiwanese adults with metabolic syndrome.BMJ open diabetes research & care · 2020Article
- Health-Related Quality of Life in Tehran Lipid and Glucose Study.International journal of endocrinology and metabolism · 2018Review
- Tobacco Smoking: Findings from 20 Years of the Tehran Lipid and Glucose Study.International journal of endocrinology and metabolism · 2018Review
- Are Obese Patients at an Increased Risk of Pelvic Floor Dysfunction Compared to Non-obese Patients?Obesity surgery · 2017Article
- Physical health-related quality of life in relation to metabolic health and obesity among men and women in Germany.Health and quality of life outcomes · 2017Article
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Authors and funding
8 authors.
Funding
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Abstract
objectiveUsing structural equation modeling, this study is one of the first efforts aimed at assessing influential factors causing gender differences in the association between health-related quality of life (HRQoL) and metabolic syndrome.
methodsA sample of 950 adults, from Tehran Lipid and Glucose Study were recruited for this cross sectional study in 2005-2007. Health-related quality of life was assessed using the Iranian version of SF-36. Metabolic syndrome components (MetSCs) and physical and mental HRQoL were considered as continuous latent constructs explaining the variances of their observed components. Structural equation modeling was performed to examine the association between the constructs of MetSCs and the physical and mental HRQoL within the two gender groups.
resultsBased on the primary hypothesis, MetSCs and HRQoL were fitted in a model. The negative effect of MetSCs on HRQoL was found to be significant only in the physical domain and only in women. The proportion of all the cardio-metabolic risk factors as well as subscales of physical HRQoL that have been explained via the two constructs of MetSCs and HRQoL, respectively, were significantly higher in women. Physical activity in both men (β = 3.19, p<0.05) and women (β = 3.94, p<0.05), age (β = -3.28, p<0.05), education (β = 2.63, p<0.05) only in women and smoking (β = 2.28, p<0.05) just in men, directly affected physical HRQoL. Regarding the mental domain, physical activity (β = 3.37, p<0.05) and marital status (β = 3.44, p<0.05) in women and age (β = 2.01, p<0.05) in men were direct effective factors. Age and education in women as well as smoking in men indirectly affected physical HRQoL via MetSCs.
conclusionGender differences in the association between MetSCs and physical HRQoL could mostly be attributed to the different structures of both MetSCs and physical HRQoL constructs in men and women. Age and smoking are the most important socio-behavioral factors which could affect this gender-specific association in the mental domain.
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