ArticlePloS one2015
Disability and Living with HIV: Baseline from a Cohort of People on Long Term ART in South Africa.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
36 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Social and Structural Determinants of Household Support for ART Adherence in Low- and Middle-Income Countries: A Systematic Review .International journal of environmental research and public health · 2020Pooled it
- A Systematic Review of Access to General Healthcare Services for People with Disabilities in Low and Middle Income Countries.International journal of environmental research and public health · 2018Pooled it
- The association between HIV infection, disability and lifestyle activity among middle-aged and older adults: an analytical cross-sectional study in Ivory Coast (the VIRAGE study).BMC public health · 2024Trial
- Predictors of receiving a diagnosis, referral and treatment of depression in people on antiretroviral therapy in South African primary care: a secondary analysis of data from a randomised trial.Tropical medicine & international health : TM & IH · 2020Trial
- Trial
- Five-year disability trajectories and associated factors among adults aging with HIV in the Ontario HIV Treatment Network Cohort Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026Article
- Chronic pain is associated with disability: results from a large, population-based survey in South Africa.Pain reports · 2026Article
- Effectiveness and Implementation of Adapted Physical Activity Delivery Strategies for Older Adults Living With HIV in Ivory Coast: Protocol for a Type 2 Hybrid Randomized Controlled Trial.JMIR research protocols · 2026Article
- Article
- Article
- Cognitive and mental health significantly contribute to disability in people ageing with HIV in Asia: an observational case-control study.Journal of the International AIDS Society · 2025Observational
- Disrupted HIV care during COVID-19 pandemic associated with increased disabilities among people living with HIV in Belize.Scientific reports · 2025Article
- Alcohol and falls among people with HIV infection: A view from Russia and the United States.Alcoholism, clinical and experimental research · 2022Article
- Article
- Views of community health workers on the integration of a physiotherapist into a ward-based outreach team.The South African journal of physiotherapy · 2022Article
- The Lived Experience of a Newly Diagnosed Older Person With HIV in Ukraine.Qualitative health research · 2021Article
- Comparative analysis of the health status of the population in six health zones in South Kivu: a cross-sectional population study using the WHODAS.Conflict and health · 2021Article
- A Multi-Dimensional Characterization of Aging and Wellbeing Among HIV-Positive Adults in Malawi.AIDS and behavior · 2021Article
- Longitudinal depressive and anxiety symptoms of adult injury patients in Kenya and their risk factors.Disability and rehabilitation · 2020Article
- HIV Status and Antiretroviral Therapy as Predictors of Disability among Older South Africans: Overall Association and Moderation by Body Mass Index.Journal of aging and health · 2020Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThrough access to life saving antiretroviral treatment (ART) in southern Africa, HIV has been reconceptualised as a chronic disease. This comes with new challenges of HIV-related co-morbidities and disabilities. We still lack an understanding of the types and scope of disabilities experienced by people on long term ART and how this impacts health, adherence, and livelihood. This paper describes the results of a cohort study examining the new health- and disability-related needs of the millions of people on ART in the region.
methodsData was collected from a cohort of people who had been on ART for six months or longer in a semi-urban public health care setting in South Africa. 1042 adults (18 and older) participated in the cross-sectional study which investigated disabilities/activity limitations, health, ART adherence, depression symptoms, and livelihood. We analysed the associations between these constructs using descriptive statistics, and bivariate and multivariate analyses.
resultsA large number of participants (35.5%) obtained a weighted score of two or more on the WHODAS 2.0 indicating possible activity limitations. A positive relationship was found between activity limitations and depression symptoms, adherence, and worse health outcomes, while none was found for BMI or CD4 count. These associations varied by type of activity limitations and, in some cases, by gender.
conclusionActivity limitations are potentially experienced by a large portion of people on ART in southern Africa which impacts health and ART adherence negatively. These results highlight the importance of better understanding the new health-related needs of people who are on long term ART, as well as the nuances of the disability they experience. This is urgently needed in order to enable HIV-endemic countries to better prepare for the new health-related needs of the millions of people on ART in southern Africa.
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