Evidence map›Paper›PMID 26624616›Full record

ArticlePLoS neglected tropical diseases2015

Long Term Control of Scabies Fifteen Years after an Intensive Treatment Programme.

Michael Marks, Betty Taotao-Wini, Lorraine Satorara, Daniel Engelman, Titus Nasi, David C Mabey, Andrew C Steer

Open access · goldAbstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 3 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 44 citations in OpenAlex.

  1. Mass Drug Administration for the Control of Scabies: A Systematic Review and Meta-analysis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Randomized Trial of Community Treatment With Azithromycin and Ivermectin Mass Drug Administration for Control of Scabies and Impetigo.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019
    Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Mass drug administration for endemic scabies: a systematic review.Tropical diseases, travel medicine and vaccines · 2021
    Review
  12. Article
  13. Paediatrics: how to manage scabies.Drugs in context · 2021
    Review
  14. Article
  15. Review
  16. Prevalence of Scabies and Impetigo 3 Years After Mass Drug Administration With Ivermectin and Azithromycin.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Article
  17. Article
  18. Control Strategies for Scabies.Tropical medicine and infectious disease · 2018
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Michael MarksClinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.
Betty Taotao-WiniDepartment of Paediatrics, National Referral Hospital, Ministry of Health and Medical Services, Honiara, Solomon Islands.
Lorraine SatoraraNational Health Training Research Institute, Ministry of Health and Medical Services, Honiara, Solomon Islands.
Daniel EngelmanCentre for International Child Health, University of Melbourne, Melbourne, Victoria, Australia.
Titus NasiDepartment of Paediatrics, National Referral Hospital, Ministry of Health and Medical Services, Honiara, Solomon Islands.
David C MabeyClinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.
Andrew C SteerCentre for International Child Health, University of Melbourne, Melbourne, Victoria, Australia.
Hospital for Tropical Diseases · GBMurdoch Children's Research Institute · AURoyal London Hospital · GBUniversity of Melbourne · AU

Funding

Wellcome Trust 100714Wellcome Trust 102807Wellcome Trust WT 102807
6 · The paper itself

Abstract

introductionScabies is a major public health problem in the Pacific and is associated with an increased risk of bacterial skin infections, glomerulonephritis and rheumatic fever. Mass drug administration with ivermectin is a promising strategy for the control of scabies. Mass treatment with ivermectin followed by active case finding was conducted in five communities in the Solomon Islands between 1997 and 2000 and resulted in a significant reduction in the prevalence of both scabies and bacterial skin infections.

methodsWe conducted a prospective follow-up study of the communities where the original scabies control programme had been undertaken. All residents underwent a standardised examination for the detection of scabies and impetigo.

resultsThree hundred and thirty eight residents were examined, representing 69% of the total population of the five communities. Only 1 case of scabies was found, in an adult who had recently returned from the mainland. The prevalence of active impetigo was 8.8% overall and 12.4% in children aged 12 years or less. DISCUSSION: We found an extremely low prevalence of scabies 15 years after the cessation of a scabies control programme. The prevalence of impetigo had also declined further since the end of the control programme. Our results suggest that a combination of mass treatment with ivermectin and intensive active case finding may result in long term control of scabies. Larger scale studies and integration with other neglected tropical disease control programmes should be priorities for scabies control efforts.

Indexed as

AdolescentAdultChildCommunicable Disease ControlFemaleFollow-Up StudiesHumansImpetigoInsecticidesIvermectinMaleMelanesiaPrevalenceProspective StudiesScabiesYoung AdultInsecticidesIvermectin

Identifiers

PMID26624616
PMCPMC4666486
OpenAlexW2187394260

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.