ArticleJournal of the American Chemical Society2015
Enantioselective Dehydrogenative Heck Arylations of Trisubstituted Alkenes with Indoles to Construct Quaternary Stereocenters.
Article in Journal of the American Chemical Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed.
- Palladium-catalyzed enantioselective alkenylation of acyclic alkenols: Broad scope with alkenyl bromides.Science advances · 2026Article
- Iridium-Catalyzed Enantioselective Alkene Hydroalkylation via a Heteroaryl-Directed Enolization-Decarboxylation Sequence.Journal of the American Chemical Society · 2023Article
- Immobilization of Trifluoromethyl-Substituted Pyridine-Oxazoline Ligand and Its Application in Asymmetric Continuous Flow Synthesis of Benzosultams.The Journal of organic chemistry · 2023Article
- Predicting relative efficiency of amide bond formation using multivariate linear regression.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Open questions on the transfer of chirality.Communications chemistry · 2021Article
- Stereoselective Remote Functionalization via Palladium-Catalyzed Redox-Relay Heck Methodologies.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021Review
- Development and Mechanistic Interrogation of Interrupted Chain-Walking in the Enantioselective Relay Heck Reaction.Journal of the American Chemical Society · 2020Article
- Transition State Force Field for the Asymmetric Redox-Relay Heck Reaction.Journal of the American Chemical Society · 2020Article
- Enantioselective Synthesis of Alkyl Allyl Ethers via Palladium-Catalyzed Redox-Relay Heck Alkenylation ofIsrael journal of chemistry · 2020Article
- Quantitative Structure-Selectivity Relationships in Enantioselective Catalysis: Past, Present, and Future.Chemical reviews · 2020Review
- Enantioselective Synthesis of γ-Functionalized Cyclopentenones and δ-Functionalized Cycloheptenones Utilizing a Redox-Relay Heck Strategy.Advanced synthesis & catalysis · 2020Article
- Synthesis of Unsaturated Silyl HeterocyclesOrganometallics · 2019Article
- Palladium-Catalyzed Reductive Heck Coupling of Alkenes.Trends in chemistry · 2019Article
- Metal-free oxidative cross-dehydrogenative coupling of quinones with benzylic C(spRSC advances · 2019Article
- Palladium-Catalyzed Enantioselective Alkenylation of Enelactams Using a Relay Heck Strategy.Chemistry (Weinheim an der Bergstrasse, Germany) · 2019Article
- Palladium-catalyzed enantioselective alkenylation of alkenylbenzene derivatives.Chemical science · 2019Article
- Enantioselective N-Alkylation of Indoles via an Intermolecular Aza-Wacker-Type Reaction.Journal of the American Chemical Society · 2019Article
- Cyclometalated Iridium-PhanePhos Complexes Are Active Catalysts in Enantioselective Allene-Fluoral Reductive Coupling and Related Alcohol-Mediated Carbonyl Additions That Form Acyclic Quaternary Carbon Stereocenters.Journal of the American Chemical Society · 2019Article
- 11-Step Total Synthesis of Teleocidins B-1-B-4.Journal of the American Chemical Society · 2019Article
- Enantioselective C2-Alkylation of Indoles through a Redox-Relay Heck Reaction of 2-Indole Triflates.Chemistry (Weinheim an der Bergstrasse, Germany) · 2019Article
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Authors and funding
4 authors.
Funding
Abstract
An enantioselective, intermolecular dehydrogenative Heck arylation of trisubstituted alkenes to construct remote quaternary stereocenters has been developed. Using a new chiral pyridine oxazoline ligand, good to high enantioselectivity is achieved for various combinations of indole derivatives and trisubstituted alkenes. However, some combinations of substrates led to lower enantioselectivity, which provided the impetus to use structure enantioselectivity correlations to design a better performing ligand.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.