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ArticlePLoS neglected tropical diseases2015

Socio-economic and Climate Factors Associated with Dengue Fever Spatial Heterogeneity: A Worked Example in New Caledonia.

Magali Teurlai, Christophe Eugène Menkès, Virgil Cavarero, Nicolas Degallier, Elodie Descloux, Jean-Paul Grangeon, Laurent Guillaumot, Thérèse Libourel, Paulo Sergio Lucio, Françoise Mathieu-Daudé and 1 more

Abstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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  10. The Effect of Increased Temperature on Dengue Virus in the VectorTropical medicine and infectious disease · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Magali TeurlaiEpidemiology of Infectious Diseases, Institut Pasteur, Noumea, New Caledonia.
Christophe Eugène MenkèsUMR 182, LOCEAN, Institute for Research and Development (IRD), Noumea, New Caledonia.
Virgil CavareroMétéo-France, Noumea, New Caledonia.
Nicolas DegallierUMR 182, Laboratoire d'Océanographie et du Climat, Expérimentation et Approches Numériques (LOCEAN), Institute for Research and Development (IRD), Paris, France.
Elodie DesclouxDepartment of Internal Medicine and Infectious Diseases, Territorial Hospital Centre, Noumea, New Caledonia.
Jean-Paul GrangeonHealth Department, Direction of Health and Social Affairs of New Caledonia, Noumea, New Caledonia.
Laurent GuillaumotMedical Entomology, Institut Pasteur, Noumea, New Caledonia.
Thérèse LibourelUMR 228, ESPACE-DEV, Université de Montpellier II, IRD, Montpellier, France.
Paulo Sergio LucioCentro de Ciências Exatas e da Terra (CCET), Universidade Federal do Rio Grande do Norte (UFRN), Campus Universitário-Lagoa Nova, Brazil.
Françoise Mathieu-DaudéUMR 224 MIVEGEC, Institute for Research and Development (IRD), Noumea, New Caledonia.
Morgan MangeasUMR 228, ESPACE-DEV, Université de Montpellier II, IRD, Montpellier, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesUnderstanding the factors underlying the spatio-temporal distribution of infectious diseases provides useful information regarding their prevention and control. Dengue fever spatio-temporal patterns result from complex interactions between the virus, the host, and the vector. These interactions can be influenced by environmental conditions. Our objectives were to analyse dengue fever spatial distribution over New Caledonia during epidemic years, to identify some of the main underlying factors, and to predict the spatial evolution of dengue fever under changing climatic conditions, at the 2100 horizon.

methodsWe used principal component analysis and support vector machines to analyse and model the influence of climate and socio-economic variables on the mean spatial distribution of 24,272 dengue cases reported from 1995 to 2012 in thirty-three communes of New Caledonia. We then modelled and estimated the future evolution of dengue incidence rates using a regional downscaling of future climate projections.

resultsThe spatial distribution of dengue fever cases is highly heterogeneous. The variables most associated with this observed heterogeneity are the mean temperature, the mean number of people per premise, and the mean percentage of unemployed people, a variable highly correlated with people's way of life. Rainfall does not seem to play an important role in the spatial distribution of dengue cases during epidemics. By the end of the 21st century, if temperature increases by approximately 3 °C, mean incidence rates during epidemics could double.

conclusionIn New Caledonia, a subtropical insular environment, both temperature and socio-economic conditions are influencing the spatial spread of dengue fever. Extension of this study to other countries worldwide should improve the knowledge about climate influence on dengue burden and about the complex interplay between different factors. This study presents a methodology that can be used as a step by step guide to model dengue spatial heterogeneity in other countries.

Indexed as

EpidemicsAedesAnimalsClimateClimate ChangeDengueEnvironmentFemaleHumansIncidenceInsect VectorsModels, BiologicalMultivariate AnalysisNew CaledoniaRainSocioeconomic Factors

Identifiers

PMID26624008
PMCPMC4666598

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.