Evidence map›Paper›PMID 26623693›Full record

ArticleAmerican journal of respiratory and critical care medicine2015

Risk-based Heterogeneity of Treatment Effect in Trials and Implications for Surveillance of Clinical Effectiveness Using Regression Discontinuity Designs.

Allan J Walkey, Jacob Bor

Registry-linked trialAbstract readComment
In one paragraph

Article in American journal of respiratory and critical care medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02843685 (Regression Discontinuity Designs to Evaluate Real-world Effectiveness), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02843685 completednot on this map

Regression Discontinuity Designs to Evaluate Real-world Effectiveness: a Case Study of Drotrecogin Alpha

TypeobservationalSponsorBoston Medical CenterRan2002Enrolled12,492ConditionsSepsisArmsDrotrecogin alfa activated
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Allan J Walkey1 Boston University School of Medicine Boston, Massachusetts.ORCID http://orcid.org/0000-0003-4685-6894
Jacob Bor2 Boston University School of Public Health Boston, Massachusetts.

Funding

Atrial Fibrillation in Sepsis: Patient Outcomes and Provider Practice PatternsK01HL116768 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI WALKEY, ALLAN J. · 2013 to 2017
$742k
NHLBI NIH HHS K01 HL116768
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Critical CareFemaleHumansMaleRandomized Controlled Trials as TopicRespiratory InsufficiencySepsis

Identifiers

PMID26623693
PMCPMC4731705

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.