Evidence map›Paper›PMID 26622990›Full record

ReviewInternational journal of preventive medicine2014

Prevention and Management of Chronic Hepatitis B.

Mamatha Bhat, Peter Ghali, Marc Deschenes, Philip Wong

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in International journal of preventive medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06589167 (Metabolic Dysfunction Among Egyptian Patients with Chronic HBV), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06589167 not yet recruitingnot on this mapstarted 2024, after this paper: background citation

Metabolic Dysfunction Among Egyptian Patients with Chronic HBV

TypeobservationalSponsorAssiut UniversityRan2024 to 2025Enrolled100ConditionsMetabolic Syndrome, Fatty Liver Disease
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Association between Severity of Liver Disease, Frequency ofThe American journal of tropical medicine and hygiene · 2018
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mamatha BhatMcGill University Health Centre, Royal Victoria Hospital, Montréal, Quebec, H3A 1A1, Canada.
Peter GhaliMcGill University Health Centre, Royal Victoria Hospital, Montréal, Quebec, H3A 1A1, Canada.
Marc DeschenesMcGill University Health Centre, Royal Victoria Hospital, Montréal, Quebec, H3A 1A1, Canada.
Philip WongMcGill University Health Centre, Royal Victoria Hospital, Montréal, Quebec, H3A 1A1, Canada.
Royal Victoria Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic hepatitis B virus (HBV) infection affects an estimated 370 million people worldwide. HBV is endemic throughout the world, and insidiously causes liver damage over years and decades without any warning symptoms or signs. Up to 25-35% of infected individuals eventually die due to complications of liver cirrhosis and hepatocellular carcinoma (HCC) induced by HBV. Screening those individuals at risk of acquiring hepatitis B, and universal vaccination for prevention, would help in limiting the spread and public health repercussions of the virus. Although many new antiviral therapies have been developed for the management of hepatitis B, they still do not offer the possibility of cure. Most individuals who begin oral suppressive therapy will be indefinitely treated. Continuous suppression of HBV replication in individuals with advanced liver disease prolongs life, decreases the need for liver transplantation, and potentially reduces the risk for HCC. In this clinical review, we present a practical approach to prevention of HBV, its natural history and life cycle, as well as its management.

Indexed as

Antiviral treatmentdiagnosishepatitis Bprevention

Identifiers

PMID26622990
PMCPMC4635410
OpenAlexW2248148595

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.