Evidence map›Paper›PMID 26622708›Full record

ArticleOncology letters2015

A case of CD10-negative angioimmunoblastic T cell lymphoma with leukemic change and increased plasma cells mimicking plasma cell leukemia: A case report.

Yasushi Adachi, Takuya Hino, Masahiko Ohsawa, Kazuhito Ueki, Tomoko Murao, Ming Li, Yunze Cui, Mitsuhiko Okigaki, Mitsuhiro Ito, Susumu Ikehara

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Yasushi AdachiDivision of Surgical Pathology, Toyooka Hospital, Toyooka City, Hyogo 668-8501, Japan ; Department of Stem Cell Disorders, Kansai Medical University, Hirakata City, Osaka 573-1010, Japan.
Takuya HinoDepartment of Internal General Medicine, Toyooka Hospital, Toyooka City, Hyogo 668-8501, Japan.
Masahiko OhsawaDepartment of Diagnostic Pathology, Osaka City University Graduate School of Medicine, Osaka City, Osaka 545-0051, Japan.
Kazuhito UekiDepartment of Internal General Medicine, Toyooka Hospital, Toyooka City, Hyogo 668-8501, Japan.
Tomoko MuraoDepartment of Clinical Laboratory, Toyooka Hospital, Toyooka City, Hyogo 668-8501, Japan.
Ming LiDepartment of Stem Cell Disorders, Kansai Medical University, Hirakata City, Osaka 573-1010, Japan.
Yunze CuiDepartment of Stem Cell Disorders, Kansai Medical University, Hirakata City, Osaka 573-1010, Japan ; Japan Immunoresearch Laboratories Co. Ltd., Takasaki City, Gunma 370-0021, Japan.
Mitsuhiko OkigakiDepartment of Internal Medicine, Otokoyama Hospital, Yawata City, Kyoto 614-8366, Japan.
Mitsuhiro ItoDivision of Medical Biophysics, Kobe University Graduate School of Health Sciences, Kobe City, Hyogo 650-0017, Japan.
Susumu IkeharaDepartment of Stem Cell Disorders, Kansai Medical University, Hirakata City, Osaka 573-1010, Japan.
Toyooka Hospital · JPKansai Medical University · JPKobe University · JPOsaka City University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Angioimmunoblastic T cell lymphoma (AITL) is a peripheral T cell lymphoma, known to express CD3 and CD4, and, frequently, also CD10 and c-Maf-1. Hypergammaglobulinemia is not particularly rare in patients with AITL. However, AITL in conjunction with plasmacytosis in the peripheral blood is rare. The current report presents a case of CD10-negative AITL demonstrating leukemic change and plasmacytosis in the peripheral blood mimicking plasma cell leukemia. A 78-year-old male was admitted to hospital due to systemic lymph node enlargement, high serum IgG and IgA, and increased counts of plasmacytoid cells and lymphoid cells with atypical nuclei in the peripheral blood. Initially, plasma cell leukemia was suspected, due to the extreme increase in the number of plasma cells in the peripheral blood. However, the plasma cells did not show clonal expansion on examination by flow cytometry. Based on histological analyses, following a biopsy of an enlarged lymph node, the patient was diagnosed with AITL. This case suggests that when hypergammaglobulinemia and increases in B-lineage cells are observed, AITL should be considered in addition to disorders of B-lineage cells.

Indexed as

angioimmunoblastic T cell lymphomabone marrowhypergammaglobulinemialeukemic changelymph nodeperipheral bloodplasmacytosis

Identifiers

PMID26622708
PMCPMC4533736
OpenAlexW2101689202

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.