ArticleOncology letters2015
Clinical value of elasticity imaging and contrast-enhanced ultrasound in the diagnosis of papillary thyroid microcarcinoma.
Article in Oncology letters, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Performance of contrast-enhanced ultrasound (CEUS) in assessing thyroid nodules: a systematic review and meta-analysis using histological standard of reference.La Radiologia medica · 2020Pooled it
- Pooled it
- Diagnostic efficacy of the contrast-enhanced ultrasound thyroid imaging reporting and data system classification for benign and malignant thyroid nodules.Quantitative imaging in medicine and surgery · 2024Article
- The predictive models based on multimodality ultrasonography for the differential diagnosis of thyroid nodules smaller than 10 mm.The British journal of radiology · 2023Article
- Value of CEUS features in diagnosing thyroid nodules with halo sign on B-mode ultrasound.BMC medical imaging · 2023Article
- Systematic review and meta-analysis: diagnostic value of different ultrasound for benign and malignant thyroid nodules.Gland surgery · 2022Article
- Performance of Contrast-Enhanced Ultrasound in Thyroid Nodules: Review of Current State and Future Perspectives.Cancers · 2021Review
- Risk Factor Analysis for Central Lymph Node Metastasis in Papillary Thyroid Microcarcinoma.International journal of general medicine · 2021Article
- Clinical applications of Doppler ultrasonography for thyroid disease: consensus statement by the Korean Society of Thyroid Radiology.Ultrasonography (Seoul, Korea) · 2020Article
- Differential diagnosis of thyroid nodules through a combination of multiple ultrasonography techniques: A decision-tree model.Experimental and therapeutic medicine · 2020Article
- Diagnostic value of fine-needle aspiration combined with ultrasound for thyroid cancer.Oncology letters · 2019Article
- Comparison of diagnostic values between ultrasound elastography and ultrasound-guided thyroid nodular puncture in thyroid nodules.Oncology letters · 2018Article
- Application of contrast-enhanced ultrasound for evaluation of thyroid nodules.Ultrasonography (Seoul, Korea) · 2018Article
- Influence of tumor extent on central lymph node metastasis in solitary papillary thyroid microcarcinomas: a retrospective study of 1092 patients.World journal of surgical oncology · 2017Article
- Ultrasonic features of papillary thyroid microcarcinoma coexisting with a thyroid abnormality.Oncology letters · 2016Article
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study aimed to evaluate the value of elasticity imaging and contrast-enhanced ultrasonography (CEUS) in the differential diagnosis of papillary thyroid microcarcinoma (TMC). In total, 73 patients exhibiting a total of 80 small thyroid nodules, which were difficult to diagnose using conventional ultrasonography, underwent elasticity imaging and CEUS. The diagnostic findings were subsequently clarified by intraoperative and pathological examination, and the accuracy of the 2 diagnostic methods was compared. The correct diagnostic rate of CEUS was 85% (68/80 nodules), of which 6 cases of TMC were misdiagnosed as benign lesions and 6 benign nodules were misdiagnosed as TMC. By contrast, the accuracy rate of the elasticity imaging, based on the 5-point diagnostic method, was 92.5% (74/80 nodules), of which 3 cases of TMC were misdiagnosed as benign nodules and 3 benign nodules were misdiagnosed as TMC. Furthermore, elasticity imaging in the diagnosis of TMC was determined to have sensitivity, specificity and accuracy rates of 94.0, 90.0 and 92.5%, respectively, whereas the corresponding rates for CEUS were 88.0, 80.0 and 85.0%, respectively. Thus, ultrasonographic elasticity imaging exhibited significant advantages in the diagnosis of TMC compared with CEUS (P<0.05). The use of CEUS demonstrates no evident advantage in the diagnosis of TMC; however, an elasticity score of ≥3 is of high clinical value as a diagnostic criterion for TMC.
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