ArticleOncology letters2015
Breast carcinoma metastasis to the lacrimal gland: Two case reports.
Article in Oncology letters, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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Who cites it
6 citing papers in PubMed, 13 citations in OpenAlex.
- Lacrimal gland pleomorphic adenoma: two referral center analyses in Hokkaido, Japan.International journal of ophthalmology · 2025Article
- Bilateral swelling of the lacrimal glands as first manifestation of systemic sarcoidosis in a patient with breast cancer.Radiology case reports · 2024Article
- [Metastasis in the periocular region].Die Ophthalmologie · 2024Review
- Eye metastasis in breast cancer: case report and review of literature.Ecancermedicalscience · 2022Article
- Masses of the Lacrimal Gland: Evaluation and Treatment.Journal of neurological surgery. Part B, Skull base · 2021Article
- Lacrimal Sac Metastasis from Phyllodes Tumor of the Breast.Korean journal of ophthalmology : KJO · 2020Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A 77-year-old female, with proptosis, reduced eye motility and diplopia which had developed over two to three months and a 69-year-old female with proptosis, oedema of the eyelid, reduced motility and ptosis, which had developed over three weeks, are presented in the present study. Computed tomography scans revealed irregular lacrimal gland tumours in the two patients. The two patients had history of breast cancer. The first breast cancer metastasis in the lacrimal gland demonstrated a cribriform growth pattern containing ductal elements. The epithelial tumour cells stained positive for cytokeratin (1-8, 10, 14-16, 18 and 19), oestrogen receptor, epithelial membrane antigen (EMA), carcinoembryonic antigen (CEA) and gross cystic disease fluid protein 15 (GCDFP-15). The second metastatic tumour was positive for EMA and estrogen receptor, but variably positive for CEA and GCDFP-15. The metastasis in the lacrimal gland was a pleomorphic tumour. The tumour cells were positive for EMA and variably positive for oestrogen and CEA. Metastases to the lacrimal gland are extremely rare, and metastases to the lacrimal gland should be considered in the diagnoses of lacrimal gland tumours. The present study aimed to describe two such cases and draw attention to breast carcinomas as a differential diagnosis and the most frequent cause of lacrimal gland metastasis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.