Evidence map›Paper›PMID 26622606›Full record

ArticleOncology letters2015

Microvascular density and endothelial area correlate with Ki-67 proliferative index in surgically-treated pancreatic ductal adenocarcinoma patients.

Michele Ammendola, Rosario Sacco, Ilaria Marech, Giuseppe Sammarco, Valeria Zuccalà, Maria Luposella, Rosa Patruno, Marcella Giordano, Eustachio Ruggieri, Nicola Zizzo and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 25 citations in OpenAlex.

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  4. Molecular characteristics andFrontiers in oncology · 2026
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  19. Mast Cell-Targeted Strategies in Cancer Therapy.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Michele AmmendolaDepartment of Medical and Surgery Science, Clinical Surgery Unit, University of Catanzaro 'Magna Graecia' Medical School, Catanzaro 88100, Italy ; Surgery Unit, National Cancer Research Centre, 'Giovanni Paolo II', Bari 70124, Italy.
Rosario SaccoDepartment of Medical and Surgery Science, Clinical Surgery Unit, University of Catanzaro 'Magna Graecia' Medical School, Catanzaro 88100, Italy.
Ilaria MarechDiagnostic and Interventional Radiology Unit with Integrated Section of Translational Medical Oncology, National Cancer Research Centre, 'Giovanni Paolo II', Bari 70124, Italy.
Giuseppe SammarcoDepartment of Medical and Surgery Science, Clinical Surgery Unit, University of Catanzaro 'Magna Graecia' Medical School, Catanzaro 88100, Italy.
Valeria ZuccalàDepartment of Health Science, Pathology Unit, University of Catanzaro 'Magna Graecia' Medical School, Catanzaro 88100, Italy.
Maria LuposellaDepartment of Medical and Surgery Science, Cardiovascular Disease Unit, University of Catanzaro 'Magna Graecia' Medical School, Catanzaro 88100, Italy.
Rosa PatrunoDiagnostic and Interventional Radiology Unit with Integrated Section of Translational Medical Oncology, National Cancer Research Centre, 'Giovanni Paolo II', Bari 70124, Italy.
Marcella GiordanoDepartment of Medical and Surgery Science, Clinical Surgery Unit, University of Catanzaro 'Magna Graecia' Medical School, Catanzaro 88100, Italy.
Eustachio RuggieriSurgery Unit, National Cancer Research Centre, 'Giovanni Paolo II', Bari 70124, Italy.
Nicola ZizzoChair of Pathology, 'Aldo Moro' University of Bari, Bari 70010, Italy.
Cosmo Damiano GadaletaDiagnostic and Interventional Radiology Unit with Integrated Section of Translational Medical Oncology, National Cancer Research Centre, 'Giovanni Paolo II', Bari 70124, Italy.
Girolamo RanieriDiagnostic and Interventional Radiology Unit with Integrated Section of Translational Medical Oncology, National Cancer Research Centre, 'Giovanni Paolo II', Bari 70124, Italy.
Istituto Tumori Bari · ITMagna Graecia University · ITUniversity of Bari Aldo Moro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous experimental and clinical data have indicated that tumour cell proliferation is associated with angiogenesis; in addition, an increased microvascular density (MVD) of tumours has been associated with poor prognosis in solid and haematological malignancies. However, limited data exists regarding the association between tumour cell proliferation and angiogenesis in primary tumour tissue from pancreatic ductal adenocarcinoma (PDAC) patients; therefore, the present study aimed to investigate this association. A series of 31 PDAC patients with stage Tumour (T)

Indexed as

adjacent normal tissueangiogenesisendothelial areaKi-67 proliferation indexpancreatic ductal adenocarcinoma

Identifiers

PMID26622606
PMCPMC4509049
OpenAlexW1496470772

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.