Evidence map›Paper›PMID 26622492›Full record

ArticleExperimental and therapeutic medicine2015

Clinical characteristics and therapeutic analysis of 51 patients with Marjolin's ulcers.

Rui Shen, Jinming Zhang, Fenggang Zhang, Yongjun DU, Weiqiang Liang, Lusheng Xu, Xueliang DU, Ping Chen, Xiaodong Chen

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Metastatic Marjolin Ulcers: A Systematic Review and Single-center Experience.Plastic and reconstructive surgery. Global open · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. An odd very early marjolin's ulcer after minimal hand burn.Annals of burns and fire disasters · 2017
    Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Rui ShenDepartment of Plastic Surgery, The Second Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510120, P.R. China ; Department of Plastic Surgery, The Affiliated Foshan Hospital of Sun Yat-sen University, Foshan, Guangdong 528000, P.R. China.
Jinming ZhangDepartment of Plastic Surgery, The Second Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510120, P.R. China.
Fenggang ZhangDepartment of Plastic Surgery, The Affiliated Foshan Hospital of Sun Yat-sen University, Foshan, Guangdong 528000, P.R. China.
Yongjun DUDepartment of Plastic Surgery, The Affiliated Foshan Hospital of Sun Yat-sen University, Foshan, Guangdong 528000, P.R. China.
Weiqiang LiangDepartment of Plastic Surgery, The Second Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510120, P.R. China.
Lusheng XuDepartment of Plastic Surgery, The Affiliated Foshan Hospital of Sun Yat-sen University, Foshan, Guangdong 528000, P.R. China.
Xueliang DUDepartment of Plastic Surgery, The Affiliated Foshan Hospital of Sun Yat-sen University, Foshan, Guangdong 528000, P.R. China.
Ping ChenDepartment of Plastic Surgery, The Affiliated Foshan Hospital of Sun Yat-sen University, Foshan, Guangdong 528000, P.R. China.
Xiaodong ChenDepartment of Plastic Surgery, The Affiliated Foshan Hospital of Sun Yat-sen University, Foshan, Guangdong 528000, P.R. China.
Foshan Hospital of TCM · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Marjolin's ulcers, which are epidermoid carcinomas arising on non-healing scar tissue, may be of various pathological types, including squamous cell carcinoma. The pathogenesis of squamous cell carcinoma arising in an ulcer differs from that of the primary cutaneous squamous cell carcinoma. This squamous cell carcinoma is aggressive in nature, and has a high rate of metastasis. Between January 2001 and September 2013, 51 patients with Marjolin's ulcers were admitted to the Departments of Plastic Surgery of the Affiliated Foshan Hospital and the Second Affiliated Hospital of Sun Yat-sen University. The ulcers included 43 cases of squamous cell carcinoma, six of melanoma, one of basal cell carcinoma and one of epithelioid sarcoma. The clinical data of these patients were retrospectively analyzed. Patients were followed until mortality. Among the patients with squamous cell carcinoma, 30.23% exhibited sentinel lymph node metastasis and 11.63% had distant metastasis. Among the patients with melanoma, 66.67% had sentinel lymph node metastasis and 33.33% had distant metastasis. Sentinel lymph node metastasis was successfully detected in 11 patients with Marjolin's ulcer using

Indexed as

18F-fluorodeoxyglucose positron emission tomography-computed tomographychronic skin ulcerMarjolin's ulcermetastasissentinel lymph nodesquamous cell carcinoma

Identifiers

PMID26622492
PMCPMC4578120
OpenAlexW1920615556

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.