Evidence map›Paper›PMID 26622485›Full record

ArticleExperimental and therapeutic medicine2015

Effect of siRNA-Livin on drug resistance to chemotherapy in glioma U251 cells and CD133

Yang Liu, Qiang Guo, Hao Zhang, Gen-Hua Li, Song Feng, Xi-Zhen Yu, Ling-Sheng Kong, Lei Zhao, Feng Jin

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Cell death in glioblastoma and the central nervous system.Cellular oncology (Dordrecht, Netherlands) · 2025
    Review
  3. Article
  4. AInternational journal of molecular sciences · 2022
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Silencing theAnnals of surgical treatment and research · 2016
    Article
  10. Silencing Livin induces apoptotic and autophagic cell death, increasing chemotherapeutic sensitivity to cisplatin of renal carcinoma cells.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2016
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Yang LiuGraduate School, Tianjin Medical University, Tianjin 300070, P.R. China.
Qiang GuoDepartment of Neurosurgery, Neuro-oncology Laboratory, Affiliated Hospital of Jining Medical College, Jining, Shandong 272029, P.R. China.
Hao ZhangDepartment of Neurosurgery, Neuro-oncology Laboratory, Affiliated Hospital of Jining Medical College, Jining, Shandong 272029, P.R. China.
Gen-Hua LiDepartment of Neurosurgery, Neuro-oncology Laboratory, Affiliated Hospital of Jining Medical College, Jining, Shandong 272029, P.R. China.
Song FengGraduate School, Tianjin Medical University, Tianjin 300070, P.R. China.
Xi-Zhen YuDepartment of Neurosurgery, Neuro-oncology Laboratory, Affiliated Hospital of Jining Medical College, Jining, Shandong 272029, P.R. China.
Ling-Sheng KongDepartment of Neurosurgery, Neuro-oncology Laboratory, Affiliated Hospital of Jining Medical College, Jining, Shandong 272029, P.R. China.
Lei ZhaoDepartment of Hepatology & Infectious Disease, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, P.R. China.
Feng JinDepartment of Neurosurgery, Neuro-oncology Laboratory, Affiliated Hospital of Jining Medical College, Jining, Shandong 272029, P.R. China.
Affiliated Hospital of Jining Medical University · CNJining Medical University · CNTianjin Medical University · CNHuazhong University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the present study was to observe the effect of siRNA-Livin on the expression of multidrug resistance-associated protein (MRP) genes in a U251 cell line and U251 stem cells. CD133

Indexed as

cancer stem celldrug resistanceglioblastomaLivinmultidrug resistance-associated protein

Identifiers

PMID26622485
PMCPMC4578066
OpenAlexW2153039369

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.