Evidence map›Paper›PMID 26622334›Full record

ArticleExperimental and therapeutic medicine2015

High prevalence of diabetic retinopathy and lack of association with integrin α2 gene polymorphisms in patients with type 2 diabetes from Northeastern Mexico.

Ana Cecilia Cepeda-Nieto, María Teresa Esquivel-Contreras, Francisco Duran-Iñiguez, Mauricio Andrés Salinas-Santander, Hugo Leonid Gallardo-Blanco, Sandra Cecilia Esparza-González, Alejandro Zugasti-Cruz, Jesús Antonio Morlett-Chávez, Luis Tlaloc Córdova-Alvelais

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
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  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ana Cecilia Cepeda-NietoResearch Department, Faculty of Medicine, Autonomous University of Coahuila, Saltillo, Coahuila 25000, Mexico.
María Teresa Esquivel-ContrerasFaculty of Chemical Sciences, Autonomous University of Coahuila, Saltillo, Coahuila 25280, Mexico.
Francisco Duran-IñiguezResearch Department, Faculty of Medicine, Autonomous University of Coahuila, Saltillo, Coahuila 25000, Mexico.
Mauricio Andrés Salinas-SantanderResearch Department, Faculty of Medicine, Autonomous University of Coahuila, Saltillo, Coahuila 25000, Mexico.
Hugo Leonid Gallardo-BlancoDepartment of Biochemistry and Molecular Medicine, Faculty of Medicine, Autonomous University of Nuevo León, Monterrey, Nuevo León 64460, Mexico.
Sandra Cecilia Esparza-GonzálezResearch Department, Faculty of Medicine, Autonomous University of Coahuila, Saltillo, Coahuila 25000, Mexico.
Alejandro Zugasti-CruzFaculty of Chemical Sciences, Autonomous University of Coahuila, Saltillo, Coahuila 25280, Mexico.
Jesús Antonio Morlett-ChávezFaculty of Chemical Sciences, Autonomous University of Coahuila, Saltillo, Coahuila 25280, Mexico.
Luis Tlaloc Córdova-AlvelaisResearch Department, Faculty of Medicine, Autonomous University of Coahuila, Saltillo, Coahuila 25000, Mexico.
Universidad Autónoma de Coahuila · MXUniversidad Autónoma de Nuevo León · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic retinopathy (DR) is one of the primary causes of blindness in the working age population and is characterized by angiogenesis in the retina. Platelets have been suggested to be involved in the pathogenesis of diabetic microvascular complications. The integrin receptor for collagen/laminin, α2β1, mediates platelet primary adhesion to subendothelial tissues, which is an essential first step in thrombus formation. The gene encoding the α2 subunit of α2β1 integrin has ≥8 polymorphisms, including a

Indexed as

diabetic retinopathyMexican populationpolymorphismα2 integrin gene

Identifiers

PMID26622334
PMCPMC4508982
OpenAlexW1567705197

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.