Evidence map›Paper›PMID 26621609›Full record

ArticleHuman immunology2016

The GL service: Web service to exchange GL string encoded HLA & KIR genotypes with complete and accurate allele and genotype ambiguity.

Robert P Milius, Michael Heuer, Mike George, Jane Pollack, Jill A Hollenbach, Steven J Mack, Martin Maiers

Abstract read
In one paragraph

Article in Human immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Robert P MiliusNational Marrow Donor Program, MN, USA. Electronic address: bmilius@nmdp.org.
Michael HeuerNational Marrow Donor Program, MN, USA.
Mike GeorgeNational Marrow Donor Program, MN, USA.
Jane PollackNational Marrow Donor Program, MN, USA.
Jill A HollenbachUniversity of California, San Francisco School of Medicine, USA.
Steven J MackChildren's Hospital & Research Center Oakland, Oakland, CA, USA.
Martin MaiersNational Marrow Donor Program, MN, USA.

Funding

The Role of HLA and KIR in Rheumatoid Arthritis and Crohn's DiseaseU01AI067068 · NIAID · STANFORD UNIVERSITY · PI ERLICH, HENRY A, TRACHTENBERG, ELIZABETH A · 2005 to 2014
$10.9M
Integrated Exchange & Storage of Current and Future-Generation Immunogenomic DataR01GM109030 · NIGMS · CHILDREN'S HOSPITAL & RES CTR AT OAKLAND · PI HOLLENBACH, JILL ALLISON, MACK, STEVEN JOHN · 2014 to 2016
$919k
NIAID NIH HHS U01 AI067068NIAID NIH HHS U01AI067068NIGMS NIH HHS R01 GM109030NIGMS NIH HHS R01GM109030
6 · The paper itself

Abstract

Genotype list (GL) Strings use a set of hierarchical character delimiters to represent allele and genotype ambiguity in HLA and KIR genotypes in a complete and accurate fashion. A RESTful web service called genotype list service was created to allow users to register a GL string and receive a unique identifier for that string in the form of a URI. By exchanging URIs and dereferencing them through the GL service, users can easily transmit HLA genotypes in a variety of useful formats. The GL service was developed to be secure, scalable, and persistent. An instance of the GL service is configured with a nomenclature and can be run in strict or non-strict modes. Strict mode requires alleles used in the GL string to be present in the allele database using the fully qualified nomenclature. Non-strict mode allows any GL string to be registered as long as it is syntactically correct. The GL service source code is free and open source software, distributed under the GNU Lesser General Public License (LGPL) version 3 or later.

Indexed as

Databases, GeneticGenotypeWeb BrowserAllelesComputational BiologyGenetic LociHLA-C AntigensHumansReceptors, KIRSoftwareHLA-C AntigensReceptors, KIRGenotypeGL stringHLAKIRRESTful service

Identifiers

PMID26621609
PMCPMC4828303

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.