ArticleThe American journal of tropical medicine and hygiene2016
Sri Lankan National Melioidosis Surveillance Program Uncovers a Nationwide Distribution of Invasive Melioidosis.
Article in The American journal of tropical medicine and hygiene, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Diabetes Mellitus as a Risk Factor for Severe Disease and Mortality Among Patients with Melioidosis: A Systematic Review and Meta-Analysis.Life (Basel, Switzerland) · 2026Review
- Use of Comparative Genomics To Resolve an Unusual Case of Aminoglycoside Susceptibility in the Melioidosis Pathogen Burkholderia pseudomallei in Bangladesh.The American journal of tropical medicine and hygiene · 2024Article
- A systematic review and meta-analysis of the global prevalence and relationships amongVeterinary world · 2024Article
- A scoping review on laboratory surveillance in the WHO Southeast Asia Region: Past, present and the future.Journal of global health · 2023Article
- Biogeography and genetic diversity of clinical isolates of Burkholderia pseudomallei in Sri Lanka.PLoS neglected tropical diseases · 2021Article
- Epidemiological and Clinical Characteristics of Melioidosis Caused by Gentamicin-SusceptibleOpen forum infectious diseases · 2021Article
- Severe Sepsis with Multiorgan Failure due to Melioidosis: A Lesson to Learn.Case reports in medicine · 2021Article
- Melioidosis after a long silence in Sri Lanka: an environmental hazard and dilemma in diagnosis, with recovery and longitudinal follow-up for 13 years: a case report.Journal of medical case reports · 2020Article
- Human Melioidosis.Clinical microbiology reviews · 2020Review
- The Impact of Age and Sex on Mouse Models of Melioidosis.Pathogens (Basel, Switzerland) · 2020Article
- Melioidosis: The hazards of incomplete peer-review.PLoS neglected tropical diseases · 2019Article
- Melioidosis with a subdural collection - a case report.BMC infectious diseases · 2019Article
- The first imported case of melioidosis in a patient in central China.Emerging microbes & infections · 2019Article
- Molecular analysis of clinical Burkholderia pseudomallei isolates from southwestern coastal region of India, using multi-locus sequence typing.PLoS neglected tropical diseases · 2018Article
- Multi locus sequence typing of Burkholderia pseudomallei isolates from India unveils molecular diversity and confers regional association in Southeast Asia.PLoS neglected tropical diseases · 2018Article
- Melioidosis in Sri Lanka.Tropical medicine and infectious disease · 2018Article
- Clinical, Bacteriologic, and Geographic Stratification of Melioidosis Emerges from the Sri Lankan National Surveillance Program.The American journal of tropical medicine and hygiene · 2018Article
- Isolated septic arthritis of hip joint: a rare presentation of melioidosis. A case report.BMC research notes · 2018Article
- A case report of melioidosis complicated by infective sacroiliitis in Sri Lanka.Tropical diseases, travel medicine and vaccines · 2018Article
- Acute disseminated melioidosis giving rise to pneumonia and renal abscesses complicated with thrombotic thrombocytopenic purpura in a post partum woman: a case report.BMC research notes · 2017Article
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5 authors.
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Abstract
The epidemiologic status of melioidosis in Sri Lanka was unclear from the few previous case reports. We established laboratory support for a case definition and started a nationwide case-finding study. Suspected Burkholderia pseudomallei isolates were collated, identified by polymerase chain reaction assay, referred for Matrix Assisted Laser Desorption Ionization-Time of Flight analysis and multilocus sequence typing (MLST), and named according to the international MLST database. Between 2006 and early 2014, there were 32 patients with culture-confirmed melioidosis with an increasing annual total and a falling fatality rate. Patients were predominantly from rural communities, diabetic, and male. The major clinical presentations were sepsis, pneumonia, soft tissue and joint infections, and other focal infection. Burkholderia pseudomallei isolates came from all parts of Sri Lanka except the Sabaragamuwa Province, the south central hill country, and parts of northern Sri Lanka. Bacterial isolates belonged to 18 multilocus sequence types, one of which (ST 1137) was associated with septicemia and a single-organ focus (Fisher's exact, P = 0.004). Melioidosis is an established endemic infection throughout Sri Lanka, and is caused by multiple genotypes of B. pseudomallei, which form a distinct geographic group based upon related sequence types (BURST) cluster at the junction of the southeast Asian and Australasian clades.
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