Trial reportBMJ open2015
Patient experience of computerised therapy for depression in primary care.
Trial report in BMJ open, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 8 syntheses or guidelines pooled it, 102 citations in OpenAlex.
- Acceptability of Digital Mental Health Interventions for Depression and Anxiety: Systematic Review.Journal of medical Internet research · 2024Pooled it
- Digital Psychotherapies for Adults Experiencing Depressive Symptoms: Systematic Review and Meta-Analysis.JMIR mental health · 2024Pooled it
- Discovering Common Elements of Empirically Supported Self-Help Interventions for Depression in Primary Care: a Systematic Review.Journal of general internal medicine · 2021Pooled it
- Pooled it
- The Acceptability and Usability of Digital Health Interventions for Adults With Depression, Anxiety, and Somatoform Disorders: Qualitative Systematic Review and Meta-Synthesis.Journal of medical Internet research · 2020Pooled it
- Patient experiences of psychological therapy for depression: a qualitative metasynthesis.BMC psychiatry · 2020Pooled it
- Women's expectations and experiences regarding e-health treatment: A systematic review.Health informatics journal · 2019Pooled it
- User Acceptance of Computerized Cognitive Behavioral Therapy for Depression: Systematic Review.Journal of medical Internet research · 2017Pooled it
- Effect of AI-Based Natural Language Feedback on Engagement and Clinical Outcomes in Fully Self-Guided Internet-Based Cognitive Behavioral Therapy for Depression: 3-Arm Randomized Controlled Trial.Journal of medical Internet research · 2026Trial
- Racial Differences in the Effectiveness of Internet-Delivered Mental Health Care.Journal of general internal medicine · 2020Trial
- Trial
- Internet-Based Cognitive Behavioral Therapy for Symptoms of Depression and Anxiety Among Patients With a Recent Myocardial Infarction: The U-CARE Heart Randomized Controlled Trial.Journal of medical Internet research · 2018Trial
- Trial
- Computerised cognitive behaviour therapy (cCBT) as treatment for depression in primary care (REEACT trial): large scale pragmatic randomised controlled trial.BMJ (Clinical research ed.) · 2015Trial
- Participatory Animation for Health Promotion in Digital-Based Health Interventions: Viewpoint on Methodology and Application.Online journal of public health informatics · 2025Article
- Dropout and completion in iCBT for university students: Insights from a thematic analysis.Internet interventions · 2025Article
- A framework for designing hybrid effectiveness-implementation trials for digital health interventions.Annals of epidemiology · 2025Article
- Beyond the medical file: A scoping review on patients' perspectives on depression treatment in primary care.PloS one · 2025Article
- Prescription Digital Therapeutics for Substance Use Disorder in Primary Care: Mixed Methods Evaluation of a Pilot Implementation Study.JMIR formative research · 2024Article
- Empathy-related abnormalities among women with premenstrual dysphoric disorder: clinical and functional magnetic resonance imaging study.BJPsych open · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveTo explore patient experience of computerised cognitive behaviour therapy (cCBT) for depression in a pragmatic randomised controlled trial (Randomised Evaluation of the Effectiveness and Acceptability of Computerised Therapy, REEACT).
designQualitative semistructured interviews with 36 participants.
participantsDepressed patients with a Patient Health Questionnaire 9 of 10 or above recruited into the REEACT randomised controlled trial.
settingPrimary care settings in England.
resultsParticipant experience was on a continuum, with some patients unable or unwilling to accept psychological therapy without interpersonal contact while others appreciated the enhanced anonymity and flexibility of cCBT. The majority of patients were ambivalent, recognising the potential benefits offered by cCBT but struggling with challenges posed by the severity of their illness, lack of support and limited personalisation of programme content. Low completion rates were commonly reported, although more positive patients reported greater engagement. Both positive and ambivalent patients perceived a need for monitoring or follow-up to support completion, while negative patients reported deliberate non-adherence due to dissatisfaction with the programme. Patients also reported that severity of depression impacted on engagement, and viewed cCBT as unsuitable for patients undergoing more severe depressive episodes.
conclusionsThe study demonstrates both the unique demands and benefits of computerised therapy. cCBT was preferred by some patients and rejected by others, but the majority of patients were ambivalent about the therapy. cCBT could be offered within a menu of options in stepped care if matched appropriately to individual patients or could be offered with enhanced support to appeal to a greater number of patients. TRIAL REGISTRATION NUMBER: ISRCTN91947481.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.