Evidence map›Paper›PMID 26621509›Full record

SynthesisBMJ open2015

Depression and anxiety in ovarian cancer: a systematic review and meta-analysis of prevalence rates.

Sam Watts, Philip Prescott, Jessica Mason, Natalie McLeod, George Lewith

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMJ open, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 108 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
108citing papers in PubMed, 11 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

108 citing papers in PubMed, 11 syntheses or guidelines pooled it.

  1. Pooled it
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  7. The effects of art therapy on anxiety, depression, and quality of life in adults with cancer: a systematic literature review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Pooled it
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  11. Anxiety disorders and all-cause mortality: systematic review and meta-analysis.Social psychiatry and psychiatric epidemiology · 2016
    Pooled it
  12. Trial
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  18. Optimising ovarian cancer care: An embedded mixed methods evaluation of a national nurse-led telehealth program.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  20. Article

48 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sam WattsFaculty of Medicine, Department of Primary Care and Population Sciences, University of Southampton, Southampton, UK.
Philip PrescottDepartment of Mathematics, University of Southampton, Southampton, UK.
Jessica MasonDepartment of Urology, Royal Shrewsbury Hospitals NHS Trust, Shrewsbury, UK.
Natalie McLeodFaculty of Medicine, University of Southampton, Southampton, UK.
George LewithFaculty of Medicine, Department of Primary Care and Population Sciences, University of Southampton, Southampton, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo systematically review the literature pertaining to the prevalence of depression and anxiety in patients with ovarian cancer as a function of treatment stage.

designSystematic review and meta-analysis.

participants3623 patients with ovarian cancer from primary research investigations. PRIMARY OUTCOME MEASURE: The prevalence of depression and anxiety in patients with ovarian cancer as a function of treatment stage.

resultsWe identified 24 full journal articles that met the inclusion criteria for entry into the meta-analysis resulting in a pooled sample size of 3623 patients. The meta-analysis of prevalence rates identified pretreatment, on-treatment and post-treatment depression prevalences of 25.34% (CI 22.79% to 28.07%), 22.99% (CI 19.85% to 26.46%) and 12.71% (CI 10.14% to 15.79%), respectively. Pretreatment, on-treatment and post-treatment anxiety prevalences were 19.12% (CI 17.11% to 21.30%), 26.23% (CI 22.30% to 30.56%) and 27.09% (CI 23.10% to 31.49%).

conclusionsOur findings suggest that the prevalence of depression and anxiety in women with ovarian cancer, across the treatment spectrum, is significantly greater than in the healthy female population. With the growing emphasis on improving the management of survivorship and quality of life, we conclude that further research is warranted to ensure psychological distress in ovarian cancer is not underdiagnosed and undertreated.

Indexed as

AnxietyDepressionFemaleHumansOvarian NeoplasmsPrevalenceSurveys and QuestionnairesMENTAL HEALTH

Identifiers

PMID26621509
PMCPMC4679843

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.