Evidence map›Paper›PMID 26621252›Full record

Trial reportBMC public health2015

Socioeconomic predictors and consequences of depression among primary care attenders with non-communicable diseases in the Western Cape, South Africa: cohort study within a randomised trial.

Naomi Folb, Crick Lund, Lara R Fairall, Venessa Timmerman, Naomi S Levitt, Krisela Steyn, Max O Bachmann

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC public health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 3 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Social inequalities in antidepressant treatment outcomes: a systematic review.Social psychiatry and psychiatric epidemiology · 2020
    Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Hyperinsulinemia Associated Depression.Clinical medicine insights. Endocrinology and diabetes · 2022
    Review
  9. Review
  10. The prevalence of depression and its associated factors among patients with diabetes mellitus attending a tertiary clinic in Gaborone, Botswana.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2022
    Article
  11. Article
  12. Observational
  13. Prevalence of depressive symptoms in urban primary care settings: Botswana.African journal of primary health care & family medicine · 2021
    Article
  14. The experiences and perceptions of mental health service provision at a primary health centre in the Eastern Cape.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2021
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Naomi FolbKnowledge Translation Unit, University of Cape Town Lung Institute, Cape Town, South Africa. naomi.folb@uct.ac.za.
Crick LundAlan J Flisher Centre for Public Mental Health, Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa. Crick.Lund@uct.ac.za.
Lara R FairallKnowledge Translation Unit, University of Cape Town Lung Institute, Cape Town, South Africa. Lara.Fairall@uct.ac.za.
Venessa TimmermanKnowledge Translation Unit, University of Cape Town Lung Institute, Cape Town, South Africa. venessat@gmail.com.
Naomi S LevittDepartment of Medicine, University of Cape Town, Cape Town, South Africa. naomi.levitt@uct.ac.za.
Krisela SteynDepartment of Medicine, University of Cape Town, Cape Town, South Africa. Krisela.Steyn@uct.ac.za.
Max O BachmannNorwich Medical School, University of East Anglia, Norwich, UK. M.Bachmann@uea.ac.uk.
University of Cape Town · ZASouth African Tuberculosis Vaccine Initiative · ZAUniversity of East Anglia · GB

Funding

NHLBI NIH HHS HHSN268200900030CPHS HHS HHSN268200900030C
6 · The paper itself

Abstract

backgroundSocioeconomic predictors and consequences of depression and its treatment were investigated in 4393 adults with specified non-communicable diseases attending 38 public sector primary care clinics in the Eden and Overberg districts of the Western Cape, South Africa.

methodsParticipants were interviewed at baseline in 2011 and 14 months later, as part of a randomised controlled trial of a guideline-based intervention to improve diagnosis and management of chronic diseases. The 10-item Center for Epidemiologic Studies Depression Scale (CESD-10) was used to assess depression symptoms, with higher scores representing more depressed mood.

resultsHigher CESD-10 scores at baseline were independently associated with being less educated (p = 0.004) and having lower income (p = 0.003). CESD-10 scores at follow-up were higher in participants with less education (p = 0.010) or receiving welfare grants (p = 0.007) independent of their baseline scores. Participants with CESD-10 scores of ten or more at baseline (56 % of all participants) had 25 % higher odds of being unemployed at follow-up (p = 0.016), independently of baseline CESD-10 score and treatment status. Among participants with baseline CESD-10 scores of ten or more, antidepressant medication at baseline was independently more likely in participants who had more education (p = 0.002), higher income (p < 0.001), or were unemployed (p = 0.001). Antidepressant medication at follow up was independently more likely in participants with higher income (p = 0.023), and in clinics with better access to pharmacists (p = 0.053) and off-site drug delivery (p = 0.013).

conclusionsSocioeconomic disadvantage appears to be both a cause and consequence of depression, and may also be a barrier to treatment. There are opportunities for improving the prevention, diagnosis and treatment of depression in primary care in inequitable middle income countries like South Africa.

trial registrationThe trial is registered with Current Controlled Trials ( ISRCTN20283604 ).

Indexed as

Ambulatory Care FacilitiesDepressionPovertyPrimary Health CareSocial ClassAdultAntidepressive AgentsChronic DiseaseCohort StudiesDepressive DisorderEducational StatusFemaleHumansIncomeMaleMiddle AgedAntidepressive Agents

Identifiers

PMID26621252
PMCPMC4666155
OpenAlexW2173429244

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.