Evidence map›Paper›PMID 26620999›Full record

ArticleArthritis research & therapy2015

Aesthetic discomfort in hand osteoarthritis: results from the LIège Hand Osteoarthritis Cohort (LIHOC).

Audrey Neuprez, Olivier Bruyère, Emmanuel Maheu, Nadia Dardenne, Nansa Burlet, Pieter D'Hooghe, Stéphan Distèche, Jean-Yves Reginster

Open access · goldAbstract read
In one paragraph

Article in Arthritis research & therapy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
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  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Audrey NeuprezDepartment of Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium. audrey.neuprez@chu.ulg.ac.be.
Olivier BruyèreDepartment of Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium. olivier.bruyere@ulg.ac.be.
Emmanuel MaheuDepartment of Rheumatology, AP-HP, St. Antoine Hospital, Paris, France. emaheu@wanadoo.fr.
Nadia DardenneDepartment of Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium. ndardenne@ulg.ac.be.
Nansa BurletDepartment of Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium. nansaburlet@gmail.com.
Pieter D'HoogheDepartment of Orthopaedics and Sports Medicine, Aspetar Hospital, Doha, Qatar. pieter.orthopedie@gmail.com.
Stéphan DistècheDepartment of Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium. s.disteche@skynet.be.
Jean-Yves ReginsterDepartment of Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium. jyreginster@ulg.ac.be.
University of Liège · BEHôpital Saint-Antoine · FRQatar Orthopaedic and Sports Medicine Hospital · QA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe primary complaint of patients with hand osteoarthritis (OA) is frequently the inelegant appearance of their hands. Only one study has been conducted to assess the magnitude of and identify the determinants of aesthetic discomfort in hand OA.

methodsThe LIège Hand Osteoarthritis Cohort is a prospective cohort of 203 patients diagnosed with hand OA. At baseline, these patients rated their aesthetic discomfort on a 100-mm visual analogue scale (VAS) and used a Likert scale (range 0-7) to quantify the magnitude of their aesthetic damage.

resultsThe median value of the aesthetic discomfort VAS was 35.0 [interquartile range (Q1-Q3) 6.0-59.0]. The median damage was rated 3.0 (Q1-Q3 1.0-4.0), corresponding to a moderate level. Both were significantly (p < 0.02) associated with the female gender, the duration of hand OA, the radiological severity of OA (Verbruggen-Veys and Kellgren-Lawrence scales) and pain, disability, or stiffness [Australian Canadian Osteoarthritis Hand Index (AUSCAN) and Functional Index for Hand Osteoarthritis ]. After a stepwise analysis, the parameters correlated to the aesthetic discomfort were the presence of erosive joints (p = 0.0048), the AUSCAN score (p < 0.0001), the number of joints with severe radiological damage (p = 0.023), and gender (p = 0.0009). For aesthetic damage, the parameters associated were AUSCAN score (p < 0.0001), duration of hand OA >10 years (p = 0.001), and presence of erosive joints (p < 0.0001). Compared with patients with low aesthetic discomfort (VAS ≤33 mm), those with the highest discomfort (VAS ≥66 mm) had more erosive OA (p = 0.014), a higher Verbruggen and Veys score (p = 0.0039), and a higher AUSCAN score (p < 0.001).

conclusionsAesthetic discomfort and damage are significant complaints in patients with hand OA. The determinants of the magnitude of these are gender, radiological severity, duration of hand OA, presence of erosive joints, and impact on pain, function, and stiffness as assessed with the AUSCAN.

Indexed as

AgedAnalysis of VarianceDisability EvaluationEstheticsFemaleFinger JointHand JointsHumansMaleMiddle AgedOsteoarthritisPainPain MeasurementProspective StudiesRegression AnalysisSeverity of Illness Index

Identifiers

PMID26620999
PMCPMC4666038
OpenAlexW2184470330

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.