SynthesisClinical oral investigations2016
Does periodontal treatment have an effect on clinical and immunological parameters of periodontal disease in obese subjects? A systematic review and meta-analysis.
Synthesis in Clinical oral investigations, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Association between Periodontal Disease and Obesity: Umbrella Review.Medicina (Kaunas, Lithuania) · 2024Pooled it
- Systemic benefits of periodontal therapy in patients with obesity and periodontitis: a systematic review.Brazilian oral research · 2024Pooled it
- Clinical and microbiological evaluation of non-surgical periodontal therapy in obese and non-obese individuals with periodontitis: a 9-month prospective longitudinal study.Journal of applied oral science : revista FOB · 2020Trial
- Obesity and cathepsin S in periodontal health and disease: A prospective clinical observational study.Acta odontologica Scandinavica · 2025Observational
- The correlation between body mass index and the effectiveness of non-surgical periodontal treatment in Taiwan population.Clinical oral investigations · 2025Article
- Association between Periodontal Condition and Fat Distribution in Japanese Adults: A Cross-Sectional Study Using Check-Up Data.International journal of environmental research and public health · 2023Article
- Evolving evidence for relationships between periodontitis and systemic diseases: Position paper from the Canadian Dental Hygienists Association.Canadian journal of dental hygiene : CJDH = Journal canadien de l'hygiene dentaire : JCHD · 2022Review
- Effects of Obesity on Bone Healing in Rats.International journal of molecular sciences · 2021Article
- The level of fibroblast growth factor-2 prepared from Advanced Platelet Rich Fibrin (A-PRF) in obese Saudi subjects compared to healthy subjects.Journal of preventive medicine and hygiene · 2021Article
- Effect of Periodontitis and Toothbrushing Frequency on Obesity Onset: A Cohort Study.Medical science monitor : international medical journal of experimental and clinical research · 2019Article
- Review of obesity and periodontitis: an epidemiological view.British dental journal · 2019Review
- Drug-Loadable Calcium Alginate Hydrogel System for Use in Oral Bone Tissue Repair.International journal of molecular sciences · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimThe aim of this study was to systematically review the literature to answer the questions: (i) "Is periodontal treatment effective to improve clinical and immunological conditions in obese subjects?"; (ii) "Do obese subjects present different clinical and immunological response after periodontal therapy when compared to non-obese subjects?"
methodsSearches were performed in six databases up to August 2014. Interventional studies were included if the following data were described: (1) Obesity/overweight assessment; (2) definition of periodontal disease; (3) periodontal therapy; (4) inflammatory marker in serum/plasma, and/or clinical parameters of periodontal disease. Assessment of quality was performed with the Downs and Black scale. Meta-analyses were conducted with the available data.
resultsOf 489 articles, 5 were included, and only 3 proceeded to meta-analysis of clinical outcomes. Included studies presented fair methodological quality. Statistical analysis demonstrated that periodontal therapy in obese subjects was effective to improve clinical outcomes. No clinical differences between post-therapy results of obese and non-obese were observed. Effects of periodontal therapy on inflammatory markers remain unclear.
conclusionsPeriodontal treatment seems to be effective to improve healing in obese individuals. No differences on periodontal healing between obese and non-obese subjects were observed; however, only limited and fragile base of evidence was available for analysis. CLINICAL RELEVANCE: Periodontal treatment is effective to improve clinical and immunological periodontal parameters in adults. Also, obesity seems to not modify the periodontal healing after treatment.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.