ArticleClinical oral investigations2016
Influence of metabolic-linked early life factors on the eruption timing of the first primary tooth.
Article in Clinical oral investigations, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 40 citations in OpenAlex.
- Early Weight Gain Forecasts Accelerated Eruption of Deciduous Teeth and Later Overweight Status during the First Year.The Journal of pediatrics · 2020Trial
- Primary tooth emergence in young children is associated with a stress biomarker.Journal of developmental origins of health and disease · 2026Article
- Association between maternal serum levels of Alpha-Fetoprotein and eruption timing of the first central deciduous tooth: a cross-sectional study.The Saudi dental journal · 2025Article
- Oral Health Conditions of Preschool Children Among Birth Cohort Studies: A Scoping Review.Oral health & preventive dentistry · 2025Article
- Association of prenatal vitamin D concentration with the eruption time of the first primary tooth: A prospective cohort study.Journal of dental research, dental clinics, dental prospects · 2025Article
- Breastfeeding and parents' socioeconomic status buffer dental developmental stress in female infants.Evolution, medicine, and public health · 2025Article
- Timing of Primary Tooth Eruption in Infants Observed by Their Parents.Children (Basel, Switzerland) · 2023Article
- General correlation between neonatal factors, primary and permanent tooth eruption and their interrelation in a population in german orthodontic practices.BMC oral health · 2023Article
- Path Analysis of the Relationships between the Eruption Time of the First Primary Teeth and Various Factors in Twins.Children (Basel, Switzerland) · 2023Article
- Eruption Timing and Sequence of Primary Teeth in a Sample of Romanian Children.Diagnostics (Basel, Switzerland) · 2022Article
- Morphological variation of the deciduous second molars in the Baka Pygmies.Scientific reports · 2021Article
- Nutritional Status is Associated with Permanent Tooth Eruption in a Group of Brazilian School Children.Global pediatric health · 2021Article
- Associations of maternal, perinatal and postnatal factors with the eruption timing of the first primary tooth.Scientific reports · 2019Article
- Evaluation of eruption of deciduous teeth among infants born after low risk pregnancy compared to infants diagnosed with Intra Uterine Growth Restriction.Journal of oral biology and craniofacial researchArticle
- Effect of Neonatal Factors on the Eruption of Primary Teeth in Children: A Longitudinal Prospective Cohort Study.International journal of clinical pediatric dentistryArticle
Corrections and comments
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Authors and funding
12 authors at 5 institutions in 2 countries.
Funding
Abstract
aimEarly eruption of permanent teeth has been associated with childhood obesity and diabetes mellitus, suggesting links between tooth eruption and metabolic conditions. This longitudinal study aimed to identify pre-, peri- and postnatal factors with metabolic consequences during infancy that may affect the eruption timing of the first primary tooth (ETFT) in children from an ethnically heterogeneous population residing within the same community. MATERIAL AND
methodsParticipants were recruited (n = 1033) through the GUSTO (Growing Up in Singapore Towards healthy Outcomes) birth cohort (n = 1237). Oral examinations were performed at 3-month intervals from 6 to 18 months of age. Crude and adjusted analyses, with generalized linear modelling, were conducted to link ETFT to potential determinants occurring during pregnancy, delivery/birth and early infancy.
resultsOverall mean eruption age of the first primary tooth was 8.5 (SD 2.6) months. Earlier tooth eruption was significantly associated with infant's rate of weight gain during the first 3 months of life and increased maternal childbearing age. Compared to their Chinese counterparts, Malay and Indian children experienced significantly delayed tooth eruption by 1.2 and 1.7 months, respectively.
conclusionsInfant weight gain from birth to 3 months, ethnicity and maternal childbearing age were significant determinants of first tooth eruption timing. Early life influences can affect primary tooth development, possibly via metabolic pathways. CLINICAL RELEVANCE: Timing of tooth eruption is linked to general growth and metabolic function. Therefore, it has potential in forecasting oral and systemic conditions such as caries and obesity.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.