Evidence map›Paper›PMID 26620651›Full record

Trial reportEuropean journal of applied physiology2016

Football training in men with prostate cancer undergoing androgen deprivation therapy: activity profile and short-term skeletal and postural balance adaptations.

Jacob Uth, Therese Hornstrup, Jesper F Christensen, Karl B Christensen, Niklas R Jørgensen, Eva W Helge, Jakob F Schmidt, Klaus Brasso, Jørn W Helge, Markus D Jakobsen and 4 more

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of applied physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01711892 (A Randomized Controlled Clinical Trial on the Effects of Recreational Soccer Training in Men With Prostate Cancer Receiving Androgen Deprivation Therapy), which is not on this map. Cited by 30 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 9 pooled it
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01711892 nacompletednot on this map

A Randomized Controlled Clinical Trial on the Effects of Recreational Soccer Training in Men With Prostate Cancer Receiving Androgen Deprivation Therapy: The FC Prostate Study

TypeinterventionalSponsorUniversity of CopenhagenRan2012 to 2013Enrolled57ConditionsProstatic Neoplasms, Exercise, Soccer Training, Androgen Deprivation TherapyArmsSoccer training
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 9 syntheses or guidelines pooled it, 56 citations in OpenAlex.

  1. Effect of exercise on bone-related outcomes in patients with cancer affected by bone metastases or bone loss: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Pooled it
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  5. The effects of exercise on the bone health of people with cancer: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022
    Pooled it
  6. Pooled it
  7. Physical exercise for bone health in men with prostate cancer receiving androgen deprivation therapy: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Pooled it
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  9. The effectiveness of lifestyle interventions to reduce side effects of androgen deprivation therapy for men with prostate cancer: a systematic review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020
    Pooled it
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  13. Gender-dependent evaluation of football as medicine for prediabetes.European journal of applied physiology · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Jacob UthUniversity Hospitals Centre for Health Research (UCSF), Rigshospitalet, University of Copenhagen, Blegdamsvej 9, Copenhagen, 2100, Denmark. ju@ucsf.dk.
Therese HornstrupDepartment of Nutrition, Exercise and Sports, Copenhagen Centre for Team Sport and Health, University of Copenhagen, Nørre Allé 51, Copenhagen, 2200, Denmark.
Jesper F ChristensenCentre for Physical Activity Research, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, Copenhagen, 2100, Denmark.
Karl B ChristensenDepartment of Biostatistics, University of Copenhagen, Øster Farimagsgade 5, Copenhagen, 1014, Denmark.
Niklas R JørgensenDepartment of Clinical Biochemistry, Rigshospitalet, Research Center for Ageing and Osteoporosis, Ndr. Ringvej 57, Glostrup, 2600, Denmark.
Eva W HelgeDepartment of Nutrition, Exercise and Sports, Copenhagen Centre for Team Sport and Health, University of Copenhagen, Nørre Allé 51, Copenhagen, 2200, Denmark.
Jakob F SchmidtDepartment of Nutrition, Exercise and Sports, Copenhagen Centre for Team Sport and Health, University of Copenhagen, Nørre Allé 51, Copenhagen, 2200, Denmark.
Klaus BrassoCopenhagen Prostate Cancer Center, Department of Urology, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, Copenhagen, 2100, Denmark.
Jørn W HelgeCenter for Healthy Aging, Department of Biomedical Sciences, University of Copenhagen, Blegdamsvej 9, Copenhagen, 2100, Denmark.
Markus D JakobsenNational Research Centre for the Working Environment, Lersø Parkallé 105, Copenhagen, 2100, Denmark.
Lars L AndersenNational Research Centre for the Working Environment, Lersø Parkallé 105, Copenhagen, 2100, Denmark.
Mikael RørthDepartment of Oncology, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, Copenhagen, 2100, Denmark.
Julie MidtgaardUniversity Hospitals Centre for Health Research (UCSF), Rigshospitalet, University of Copenhagen, Blegdamsvej 9, Copenhagen, 2100, Denmark.
Peter KrustrupDepartment of Nutrition, Exercise and Sports, Copenhagen Centre for Team Sport and Health, University of Copenhagen, Nørre Allé 51, Copenhagen, 2200, Denmark.
University of Copenhagen · DKNational Research Centre for the Working Environment · DKRigshospitalet · DKUniversity of Southern Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the activity profile of football training and its short-term effects on bone mass, bone turnover markers (BTMs) and postural balance in men with prostate cancer (PCa) undergoing androgen deprivation therapy (ADT).

methodsThis was a randomised 12-week study in which men with PCa undergoing ADT were assigned to a football intervention group [FTG, n = 29, 67 ± 7 (±SD) years] training 2‒3 times per week for 45‒60 min or to a control group (n = 28, 66 ± 5 years). The activity profile was measured using a 5-Hz GPS. The outcomes were total body and leg bone mineral content (BMC) and density, BTMs and postural balance.

resultsIn the last part of the 12 weeks, FTG performed 194 ± 41 accelerations and 296 ± 65 decelerations at >0.6 m/s/s and covered a distance of 905 ± 297 m at speeds >6 km/h and 2646 ± 705 m per training session. Analysis of baseline-to-12-week change scores showed between-group differences in favour of FTG in total body BMC [26.4 g, 95 % confidence interval (CI): 5.8-46.9 g, p = 0.013], leg BMC (13.8 g, 95 % CI: 7.0‒20.5 g, p < 0.001) and markers of bone formation: P1NP (36.6 µg/L, 95 % CI: 10.4‒62.8 µg/L, p = 0.008) and osteocalcin (8.6 µg/L, 95 % CI: 3.3‒13.8 µg/L, p < 0.01). The number of decelerations correlated to the increase in leg BMC (r = 0.65, p = 0.012). No between-group differences were observed for the remaining outcomes.

conclusionFootball training involves numerous runs, accelerations and decelerations, which may be linked to marked increases in bone formation markers and preserved bone mass in middle-aged and elderly men with PCa undergoing ADT.

trial registrationClinicalTrials.gov: NCT01711892.

Indexed as

Adaptation, PhysiologicalFootballPostural BalanceAgedAndrogen AntagonistsAntineoplastic Agents, HormonalBone DensityExercise TherapyHumansMaleMiddle AgedMuscle, SkeletalProstatic NeoplasmsAndrogen AntagonistsAntineoplastic Agents, HormonalAssociation footballBone mineral content (BMC)Bone turnover markers (BTM)Exercise intensityGPSProstate cancer

Identifiers

PMID26620651
OpenAlexW2185659393

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.