ArticleCurrent microbiology2016
Detection of Quorum Sensing Molecules and Biofilm Formation in Ralstonia solanacearum.
Article in Current microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 46 citations in OpenAlex.
- Bacterial quorum-sensing systems in cell-cell communication.FEMS microbiology reviews · 2026Review
- Metabolomic Profiling of Tomato Root Exudates Induced byJournal of microbiology and biotechnology · 2025Article
- The hidden language of plant-beneficial microbes: chemo-signaling dynamics in plant microenvironments.World journal of microbiology & biotechnology · 2025Review
- Adaptation of the Endolithic Biome in Antarctic Volcanic Rocks.International journal of molecular sciences · 2023Article
- Silicon Controls Bacterial Wilt Disease in Tomato Plants and Inhibits the Virulence-Related Gene Expression ofInternational journal of molecular sciences · 2022Article
- Biocomputational Assessment of Natural Compounds as a Potent Inhibitor to Quorum Sensors inMolecules (Basel, Switzerland) · 2022Article
- Anti-Biofilm Activity and Biocontrol Potential ofIndian journal of microbiology · 2022Article
- Research progress on the pharmacological effects of matrine.Frontiers in neuroscience · 2022Review
- 1,8-Cineole inhibits biofilm formation and bacterial pathogenicity by suppressingFrontiers in pharmacology · 2022Article
- Biofilm Eradication Using Biogenic Silver Nanoparticles.Molecules (Basel, Switzerland) · 2020Article
- Genome-scale metabolic reconstruction and in silico analysis of the rice leaf blight pathogen, Xanthomonas oryzae.Molecular plant pathology · 2020Article
- Effect of the luxI/R gene on AHL-signaling molecules and QS regulatory mechanism in Hafnia alvei H4.AMB Express · 2019Article
- A genome-wide scan for genes under balancing selection in the plant pathogen Ralstonia solanacearum.BMC evolutionary biology · 2019Article
- Inhibitory Effect of Two Traditional Chinese Medicine Monomers, Berberine and Matrine, on the Quorum Sensing System of Antimicrobial-ResistantFrontiers in microbiology · 2019Article
- "In-Group" Communication in MarineFrontiers in cellular and infection microbiology · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many bacteria use small diffusible signaling molecules to communicate each other termed as quorum sensing (QS). Most Gram-negative bacteria use acyl homoserine lactone (AHL) as QS signal molecules. Using these signaling molecules, bacteria are able to express specific genes in response to population density. This work aimed to detect the production of QS signal molecules and biofilm formation in Ralstonia solanacearum isolated from various diseased tomato plants with symptoms of bacterial wilt. A total of 30 R. solanacearum strains were investigated for the production of QS signal molecules using Chromobacterium violaceum CV026 and Agrobacterium tumefaciens NT1 (pZLR4) biosensor systems. All 30 bacterial isolates from various bacterial wilt-affected tomato plants produced AHL molecules that induced the biosensor. The microtiter plate assay demonstrated that of the 30 bacterial isolates, 60 % formed biofilm, among which four isolates exhibited a higher degree of biofilm formation. The biofilm-inducing factor was purified from these four culture supernatants. The structure of the responsible molecule was solved using nuclear magnetic resonance and mass spectroscopy and was determined to be 2-hydroxy-4-((methylamino)(phenyl)methyl) cyclopentanone (HMCP), which was confirmed by chemical synthesis and NMR. The Confocal laser scanning microscopic analysis showed well-developed biofilm architecture of bacteria when treated with HMCP. The knowledge we obtained from this study will be useful for further researcher on the role of HMCP molecule in biofilm formation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.