Evidence map›Paper›PMID 26620523›Full record

ArticlePlant physiology2016

Seed Dormancy in Arabidopsis Is Controlled by Alternative Polyadenylation of DOG1.

Malgorzata Cyrek, Halina Fedak, Arkadiusz Ciesielski, Yanwu Guo, Aleksandra Sliwa, Lien Brzezniak, Katarzyna Krzyczmonik, Zbigniew Pietras, Szymon Kaczanowski, Fuquan Liu and 1 more

Open access · bronzeAbstract read
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In one paragraph

Article in Plant physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
9.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 93 citations in OpenAlex.

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  11. Light regulates widespread plant alternative polyadenylation through the chloroplast.Proceedings of the National Academy of Sciences of the United States of America · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Malgorzata CyrekInstitute of Biochemistry and Biophysics, Department of Protein Biosynthesis, Pawinskiego 5a, 02-106 Warsaw, Poland (M.C., H.F., A.C., Y.G., A.S., L.B., K.K., Z.P., S.K., S.S.); Warsaw University, Department of Chemistry, Pasteura 1, 02-093 Warsaw, Poland (A.C.); andQueen's University Belfast, School of Biological Sciences, Belfast BT9 7BL, Northern Ireland (F.L.).ORCID http://orcid.org/0000-0001-7449-8081
Halina FedakInstitute of Biochemistry and Biophysics, Department of Protein Biosynthesis, Pawinskiego 5a, 02-106 Warsaw, Poland (M.C., H.F., A.C., Y.G., A.S., L.B., K.K., Z.P., S.K., S.S.); Warsaw University, Department of Chemistry, Pasteura 1, 02-093 Warsaw, Poland (A.C.); andQueen's University Belfast, School of Biological Sciences, Belfast BT9 7BL, Northern Ireland (F.L.).
Arkadiusz CiesielskiInstitute of Biochemistry and Biophysics, Department of Protein Biosynthesis, Pawinskiego 5a, 02-106 Warsaw, Poland (M.C., H.F., A.C., Y.G., A.S., L.B., K.K., Z.P., S.K., S.S.); Warsaw University, Department of Chemistry, Pasteura 1, 02-093 Warsaw, Poland (A.C.); andQueen's University Belfast, School of Biological Sciences, Belfast BT9 7BL, Northern Ireland (F.L.).
Yanwu GuoInstitute of Biochemistry and Biophysics, Department of Protein Biosynthesis, Pawinskiego 5a, 02-106 Warsaw, Poland (M.C., H.F., A.C., Y.G., A.S., L.B., K.K., Z.P., S.K., S.S.); Warsaw University, Department of Chemistry, Pasteura 1, 02-093 Warsaw, Poland (A.C.); andQueen's University Belfast, School of Biological Sciences, Belfast BT9 7BL, Northern Ireland (F.L.).
Aleksandra SliwaInstitute of Biochemistry and Biophysics, Department of Protein Biosynthesis, Pawinskiego 5a, 02-106 Warsaw, Poland (M.C., H.F., A.C., Y.G., A.S., L.B., K.K., Z.P., S.K., S.S.); Warsaw University, Department of Chemistry, Pasteura 1, 02-093 Warsaw, Poland (A.C.); andQueen's University Belfast, School of Biological Sciences, Belfast BT9 7BL, Northern Ireland (F.L.).
Lien BrzezniakInstitute of Biochemistry and Biophysics, Department of Protein Biosynthesis, Pawinskiego 5a, 02-106 Warsaw, Poland (M.C., H.F., A.C., Y.G., A.S., L.B., K.K., Z.P., S.K., S.S.); Warsaw University, Department of Chemistry, Pasteura 1, 02-093 Warsaw, Poland (A.C.); andQueen's University Belfast, School of Biological Sciences, Belfast BT9 7BL, Northern Ireland (F.L.).
Katarzyna KrzyczmonikInstitute of Biochemistry and Biophysics, Department of Protein Biosynthesis, Pawinskiego 5a, 02-106 Warsaw, Poland (M.C., H.F., A.C., Y.G., A.S., L.B., K.K., Z.P., S.K., S.S.); Warsaw University, Department of Chemistry, Pasteura 1, 02-093 Warsaw, Poland (A.C.); andQueen's University Belfast, School of Biological Sciences, Belfast BT9 7BL, Northern Ireland (F.L.).
Zbigniew PietrasInstitute of Biochemistry and Biophysics, Department of Protein Biosynthesis, Pawinskiego 5a, 02-106 Warsaw, Poland (M.C., H.F., A.C., Y.G., A.S., L.B., K.K., Z.P., S.K., S.S.); Warsaw University, Department of Chemistry, Pasteura 1, 02-093 Warsaw, Poland (A.C.); andQueen's University Belfast, School of Biological Sciences, Belfast BT9 7BL, Northern Ireland (F.L.).
Szymon KaczanowskiInstitute of Biochemistry and Biophysics, Department of Protein Biosynthesis, Pawinskiego 5a, 02-106 Warsaw, Poland (M.C., H.F., A.C., Y.G., A.S., L.B., K.K., Z.P., S.K., S.S.); Warsaw University, Department of Chemistry, Pasteura 1, 02-093 Warsaw, Poland (A.C.); andQueen's University Belfast, School of Biological Sciences, Belfast BT9 7BL, Northern Ireland (F.L.).
Fuquan LiuInstitute of Biochemistry and Biophysics, Department of Protein Biosynthesis, Pawinskiego 5a, 02-106 Warsaw, Poland (M.C., H.F., A.C., Y.G., A.S., L.B., K.K., Z.P., S.K., S.S.); Warsaw University, Department of Chemistry, Pasteura 1, 02-093 Warsaw, Poland (A.C.); andQueen's University Belfast, School of Biological Sciences, Belfast BT9 7BL, Northern Ireland (F.L.).ORCID http://orcid.org/0000-0001-8764-6370
Szymon SwiezewskiInstitute of Biochemistry and Biophysics, Department of Protein Biosynthesis, Pawinskiego 5a, 02-106 Warsaw, Poland (M.C., H.F., A.C., Y.G., A.S., L.B., K.K., Z.P., S.K., S.S.); Warsaw University, Department of Chemistry, Pasteura 1, 02-093 Warsaw, Poland (A.C.); andQueen's University Belfast, School of Biological Sciences, Belfast BT9 7BL, Northern Ireland (F.L.) sswiez@ibb.waw.pl.
Queen's University Belfast · GBInstitute of Biochemistry and Biophysics, Polish Academy of Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DOG1 (Delay of Germination 1) is a key regulator of seed dormancy in Arabidopsis (Arabidopsis thaliana) and other plants. Interestingly, the C terminus of DOG1 is either absent or not conserved in many plant species. Here, we show that in Arabidopsis, DOG1 transcript is subject to alternative polyadenylation. In line with this, mutants in RNA 3' processing complex display weakened seed dormancy in parallel with defects in DOG1 proximal polyadenylation site selection, suggesting that the short DOG1 transcript is functional. This is corroborated by the finding that the proximally polyadenylated short DOG1 mRNA is translated in vivo and complements the dog1 mutant. In summary, our findings indicate that the short DOG1 protein isoform produced from the proximally polyadenylated DOG1 mRNA is a key player in the establishment of seed dormancy in Arabidopsis and characterizes a set of mutants in RNA 3' processing complex required for production of proximally polyadenylated functional DOG1 transcript.

Indexed as

Amino Acid SequenceArabidopsisArabidopsis ProteinsBase SequenceConserved SequenceGene Expression Regulation, PlantGerminationMolecular Sequence DataMutationPhenotypePlant DormancyPolyadenylationProtein BiosynthesisProtein IsoformsRNA, MessengerRNA Processing, Post-TranscriptionalArabidopsis ProteinsDOG1 protein, ArabidopsisProtein IsoformsRNA, Messenger

Identifiers

PMID26620523
PMCPMC4734566
OpenAlexW2190595999

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.