ArticleOsteoarthritis and cartilage2016
MR T1ρ and T2 of meniscus after acute anterior cruciate ligament injuries.
Article in Osteoarthritis and cartilage, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Evaluation of Pre-Operative Cartilage and Meniscus Ultrashort Echo Time T2* as Biomarkers of Long-Term Clinical Outcomes Following Anterior Cruciate Ligament Reconstruction.Journal of magnetic resonance imaging : JMRI · 2026Article
- In the Acute Phase of Anterior Cruciate Ligament Rupture: Quantitative Assessment of Matrix Changes and Correlation between Different States of Meniscus and Adjacent Cartilage.Orthopaedic surgery · 2024Article
- Assessment of ultrashort echo time (UTE) TQuantitative imaging in medicine and surgery · 2023Article
- Clinical application of ultrashort echo time (UTE) and zero echo time (ZTE) magnetic resonance (MR) imaging in the evaluation of osteoarthritis.Skeletal radiology · 2023Review
- Knee MRI biomarkers associated with structural, functional and symptomatic changes at least a year from ACL injury - A systematic review.Osteoarthritis and cartilage open · 2023Review
- Ultrashort echo time magnetization transfer imaging of knee cartilage and meniscus after long-distance running.European radiology · 2023Article
- Histological Findings and T2 Relaxation Time in Canine Menisci of Elderly Dogs-An Ex Vivo Study in Stifle Joints.Veterinary sciences · 2023Article
- Periodical assessment of four horns of knee meniscus using MR T2 mapping imaging in volunteers before and after amateur marathons.Scientific reports · 2022Article
- Patellar instability MRI measurements are associated with knee joint degeneration after reconstruction of the medial patellofemoral ligament.Skeletal radiology · 2022Article
- TSkeletal radiology · 2022Article
- Macromolecular fraction (MMF) from 3D ultrashort echo time cones magnetization transfer (3D UTE-Cones-MT) imaging predicts meniscal degeneration and knee osteoarthritis.Osteoarthritis and cartilage · 2021Article
- Association of Jump-Landing Biomechanics With Tibiofemoral Articular Cartilage Composition 12 Months After ACL Reconstruction.Orthopaedic journal of sports medicine · 2021Article
- Prediction of local fixed charge density loss in cartilage following ACL injury and reconstruction: A computational proof-of-concept study with MRI follow-up.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2021Article
- Patients With Abnormal Limb Kinetics at 6 Months After Anterior Cruciate Ligament Reconstruction Have an Increased Risk of Persistent Medial Meniscal Abnormality at 3 Years.Orthopaedic journal of sports medicine · 2020Article
- TEuropean radiology · 2019Observational
- Quantitative mapping of acute and chronic PCL pathology with 3 T MRI: a prospectively enrolled patient cohort.Journal of experimental orthopaedics · 2019Article
- An Abnormal Tibial Position Is Associated With Alterations in the Meniscal Matrix: A 3-Year Longitudinal Study After Anterior Cruciate Ligament Reconstruction.Orthopaedic journal of sports medicine · 2019Article
- Longitudinal changes in MR T1ρ/T2 signal of meniscus and its association with cartilage T1p/T2 in ACL-injured patients.Osteoarthritis and cartilage · 2018Article
- Temperature-corrected post-mortem 1.5 T MRI quantification of non-pathologic upper abdominal organs.International journal of legal medicine · 2017Article
- Advanced Imaging in Osteoarthritis.Sports health · 2016Review
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Authors and funding
11 authors.
Funding
Abstract
objectiveTo evaluate differences in meniscal T1ρ and T2 quantification in patients with acute anterior cruciate ligament (ACL) injuries and to determine correlations of these differences with MR morphological grading and patient-reported outcomes.
designBilateral knees of 52 patients with acute ACL injury and 20 healthy controls were scanned using 3 T magnetic resonance imaging (MRI) T1ρ and T2 mapping in this prospective study. Quantitative analysis of the meniscus was performed in anterior and posterior horns of the lateral and medial menisci. Morphological meniscal damage was assessed using modified whole-organ MRI scores (WORMS). Measurements were compared between injured, uninjured contralateral, and control knees using a mixed-effects regression model. Correlations between meniscal T1ρ/T2, WORMS and Knee Injury and Osteoarthritis Outcome Scores (KOOS) were examined using partial correlation analysis.
resultsMean meniscal T1ρ and T2 values were significantly higher in ACL-injured knees compared to control and contralateral knees. Menisci of ACL-injured knees without tears, including those limited to modified meniscal WORMS grade 0, also had significantly higher T1ρ and T2 values compared to menisci of uninjured knees. Within ACL-injured knees, T1ρ and T2 values showed significant positive associations with meniscal WORMS and significant negative associations with KOOS.
conclusionAcute ACL injuries are associated with significantly increased meniscal T1ρ and T2 values in both patients with and without meniscal lesions or tears, suggesting quantitative MRI provides more sensitive measures of meniscal differences compared to traditional morphological MRI sequences. Correlation between meniscal T1ρ/T2 and KOOS suggest that quantitative MRI is reflective of the extent of patients' clinical symptoms.
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