SynthesisPloS one2015
Long-Term Exposure to Primary Traffic Pollutants and Lung Function in Children: Cross-Sectional Study and Meta-Analysis.
Synthesis in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Pooled it
- Effect of outdoor air pollution on asthma exacerbations in children and adults: Systematic review and multilevel meta-analysis.PloS one · 2017Pooled it
- The risk of new-onset diabetes in antidepressant users - A systematic review and meta-analysis.PloS one · 2017Pooled it
- Effects of short-term exposure to air pollution on respiratory symptoms and lung function among patients with asthma.Medical gas research · 2026Article
- Impact of air pollution on lung function in cystic fibrosis over a decade in London: a UK CF Registry study.Thorax · 2026Article
- Article
- Ambient exposure to nitrogen dioxide and lung function: a multi-metric approach.Environmental monitoring and assessment · 2025Article
- Long-Term Exposure to Nitrogen Dioxide and Ozone and Respiratory Health in Children.Annals of the American Thoracic Society · 2025Article
- Article
- Long-term ozone exposure and lung function in middle childhood.Environmental research · 2024Article
- : Short-term effects of exposure to particulate matter on hospital admissions for asthma and chronic obstructive pulmonary disease.Medicine · 2022Article
- Short-term effects of exposure to particulate matter and air pollution on hospital admissions for asthma and chronic obstructive pulmonary disease in Gyeonggi-do, South Korea, 2007-2018.Journal of environmental health science & engineering · 2021Article
- Mobility in post-pandemic economic reopening under social distancing guidelines: Congestion, emissions, and contact exposure in public transit.Transportation research. Part A, Policy and practice · 2021Article
- A multi-scalar perspective on health and urban housing: an umbrella review.Buildings & cities · 2021Article
- Ambient air pollution and emergency department visits among children and adults in Casablanca, Morocco.AIMS public health · 2021Article
- Review of epidemiological studies on air pollution and health effects in children.Clinical and experimental pediatrics · 2021Article
- Impact of Air Pollution on Asthma Outcomes.International journal of environmental research and public health · 2020Review
- Residential Links to Air Pollution and School Children with Asthma in Vilnius (Population Study).Medicina (Kaunas, Lithuania) · 2020Article
- Prenatal, Early-Life, and Childhood Exposure to Air Pollution and Lung Function: The ALSPAC Cohort.American journal of respiratory and critical care medicine · 2020Article
- Influence of viral infection on the relationships between airway cytokines and lung function in asthmatic children.Respiratory research · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
backgroundThere is widespread concern about the possible health effects of traffic-related air pollution. Nitrogen dioxide (NO2) is a convenient marker of primary pollution. We investigated the associations between lung function and current residential exposure to a range of air pollutants (particularly NO2, NO, NOx and particulate matter) in London children. Moreover, we placed the results for NO2 in context with a meta-analysis of published estimates of the association. METHODS AND
findingsAssociations between primary traffic pollutants and lung function were investigated in 4884 children aged 9-10 years who participated in the Child Heart and Health Study in England (CHASE). A systematic literature search identified 13 studies eligible for inclusion in a meta-analysis. We combined results from the meta-analysis with the distribution of the values of FEV1 in CHASE to estimate the prevalence of children with abnormal lung function (FEV1<80% of predicted value) expected under different scenarios of NO2 exposure. In CHASE, there were non-significant inverse associations between all pollutants except ozone and both FEV1 and FVC. In the meta-analysis, a 10 μg/m3 increase in NO2 was associated with an 8 ml lower FEV1 (95% CI: -14 to -1 ml; p: 0.016). The observed effect was not modified by a reported asthma diagnosis. On the basis of these results, a 10 μg/m3 increase in NO2 level would translate into a 7% (95% CI: 4% to 12%) increase of the prevalence of children with abnormal lung function.
conclusionsExposure to traffic pollution may cause a small overall reduction in lung function and increase the prevalence of children with clinically relevant declines in lung function.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.