ArticleThe New phytologist2016
Genetic architecture of wood properties based on association analysis and co-expression networks in white spruce.
Article in The New phytologist, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Revealing the genetic regulation of wood traits and secondary cell wall development inHorticulture research · 2026Article
- Heterologous expression of Pinus massoniana VNS2 enhances secondary cell wall deposition in poplar.Plant cell reports · 2026Article
- Application and development prospect of genomic selection breeding in coniferous trees.Planta · 2025Review
- Genome-wide association studies in forestry.Molecular biology reports · 2025Review
- Article
- Genotyping SNPs in lignin biosynthesis gene (CAD1) and transcription factors (MYB1 and MYB2) exhibits association with wood density in teak (Tectona grandis L.f.).Molecular biology reports · 2024Article
- A transcriptome-based association study of growth, wood quality, and oleoresin traits in a slash pine breeding population.PLoS genetics · 2022Article
- Achievements and Challenges of Genomics-Assisted Breeding in Forest Trees: From Marker-Assisted Selection to Genome Editing.International journal of molecular sciences · 2021Review
- Connecting tree-ring phenotypes, genetic associations and transcriptomics to decipher the genomic architecture of drought adaptation in a widespread conifer.Molecular ecology · 2021Article
- Leveraging breeding programs and genomic data in Norway spruce (Picea abies L. Karst) for GWAS analysis.Genome biology · 2021Article
- Genetic control of tracheid properties in Norway spruce wood.Scientific reports · 2020Article
- Transcriptional analysis of arogenate dehydratase genes identifies a link between phenylalanine biosynthesis and lignin biosynthesis.Journal of experimental botany · 2020Article
- Induction of PrMADS10 on the lower side of bent pine tree stems: potential role in modifying plant cell wall properties and wood anatomy.Scientific reports · 2019Article
- Ray Parenchymal Cells Contribute to Lignification of Tracheids in Developing Xylem of Norway Spruce.Plant physiology · 2019Article
- Genome-wide association study identified novel candidate loci affecting wood formation in Norway spruce.The Plant journal : for cell and molecular biology · 2019Article
- Association genetics of acetophenone defence against spruce budworm in mature white spruce.BMC plant biology · 2018Article
- Co-expression network of transcription factors reveal ethylene-responsive element-binding factor as key regulator of wood phenotype in3 Biotech · 2018Article
- PpNAC1, a main regulator of phenylalanine biosynthesis and utilization in maritime pine.Plant biotechnology journal · 2018Article
- Drought Sensitivity of Norway Spruce at the Species' Warmest Fringe: Quantitative and Molecular Analysis Reveals High Genetic Variation Among and Within Provenances.G3 (Bethesda, Md.) · 2018Article
- The first identification of genomic loci in plants associated with resistance to galling insects: a case study in Eucalyptus L'Hér. (Myrtaceae).Scientific reports · 2018Article
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6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Association studies are widely utilized to analyze complex traits but their ability to disclose genetic architectures is often limited by statistical constraints, and functional insights are usually minimal in nonmodel organisms like forest trees. We developed an approach to integrate association mapping results with co-expression networks. We tested single nucleotide polymorphisms (SNPs) in 2652 candidate genes for statistical associations with wood density, stiffness, microfibril angle and ring width in a population of 1694 white spruce trees (Picea glauca). Associations mapping identified 229-292 genes per wood trait using a statistical significance level of P < 0.05 to maximize discovery. Over-representation of genes associated for nearly all traits was found in a xylem preferential co-expression group developed in independent experiments. A xylem co-expression network was reconstructed with 180 wood associated genes and several known MYB and NAC regulators were identified as network hubs. The network revealed a link between the gene PgNAC8, wood stiffness and microfibril angle, as well as considerable within-season variation for both genetic control of wood traits and gene expression. Trait associations were distributed throughout the network suggesting complex interactions and pleiotropic effects. Our findings indicate that integration of association mapping and co-expression networks enhances our understanding of complex wood traits.
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