Evidence map›Paper›PMID 26618199›Full record

ArticleTrends in cancer2015

Why does infection with some helminths cause cancer?

Paul J Brindley, José M Correia da Costa, Banchob Sripa

Open access · greenAbstract read
In one paragraph

Article in Trends in cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed
8.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 122 citations in OpenAlex.

  1. Article
  2. Review
  3. Food and waterborne parasitology · 2026
    Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Trematode Genomics and Proteomics.Advances in experimental medicine and biology · 2024
    Article
  17. Article
  18. Article
  19. Review
  20. Cystatins from the Human Liver FlukePathogens (Basel, Switzerland) · 2023
    Article

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Paul J BrindleyDepartment of Microbiology, Immunology and Tropical Medicine, and Research Center for Neglected Diseases of Poverty, School of Medicine & Health Sciences, George Washington University, Washington, DC 20037, USA.
José M Correia da CostaCenter for Parasite Biology and Immunology, National Institute of Health Dr. Ricardo Jorge, Rua Alexandre Herculano, 321, 4000-055 Porto, Portugal; and Center for the Study of Animal Science, CECA/ICETA, University of Porto, Portugal.
Banchob SripaTropical Disease Research Laboratory, Department of Pathology, and Liver Fluke and Cholangiocarcinoma Research Center, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
George Washington University · USKhon Kaen University · THNational Institute of Health Dr. Ricardo Jorge · PT

Funding

Targeting parasite-host communication to combat liver fluke-induced bile duct cancerR01CA164719 · NCI · GEORGE WASHINGTON UNIVERSITY · PI Paul J Brindley, THEWARACH LAHA · 2012 to 2026
$5.0M
Biomarkers of Opisthorchis viverrini-induced cholangiocarcinomaR01CA155297 · NCI · GEORGE WASHINGTON UNIVERSITY · PI BETHONY, JEFFREY MICHAEL, BRINDLEY, PAUL J · 2011 to 2015
$2.7M
Pathogenesis of Opisthorchiasis induced persistent periductal fibrosis and CCAP50AI098639 · NIAID · KHON KAEN UNIVERSITY · PI SRIPA, BANCHOB · 2012 to 2016
$1.6M
NCI NIH HHS R01 CA155297NCI NIH HHS R01 CA164719NIAID NIH HHS P50 AI098639
6 · The paper itself

Abstract

Infections with

Indexed as

carcinogenesiscatechol estrogen quinonecholangiocarcinomadepurinating DNA adducthelminth parasitesInfection-related canceropisthorchiasisoxysterolsquamous cell cancer of the bladderurogenital schistosomiasis

Identifiers

PMID26618199
PMCPMC4657143
OpenAlexW1869256893

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.