ArticleJACC. Clinical electrophysiology2015
Intentional Right Atrial Exit and Carbon Dioxide Insufflation to Facilitate Subxiphoid Needle Entry Into the Empty Pericardial Space: First Human Experience.
Article in JACC. Clinical electrophysiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 30 citations in OpenAlex.
- Multicenter Coronary Venous Carbon Dioxide Insufflation for Subxiphoid Epicardial Access in Ventricular Tachycardia Ablation.JACC. Asia · 2026Article
- Left Atrial Appendage Occlusion vs. Oral Anticoagulants: Current Evidence and Debates.Journal of clinical medicine · 2026Review
- Feasibility, safety, and efficacy of epicardial COHeart rhythm O2 · 2026Article
- Advances in Epicardial Access for Ventricular Tachycardia Ablation: From Historical Techniques to Carbon Dioxide Insufflation.Reviews in cardiovascular medicine · 2026Review
- Ventricular Intramyocardial Navigation for Tachycardia Ablation Guided by Electrograms (VINTAGE): Initial Human Experience.JACC. Clinical electrophysiology · 2025Article
- Transcatheter Coronary Artery Bypass to Circumvent Iatrogenic Obstruction: The VECTOR (Ventriculo-Coronary Transcatheter Outward Navigation and Re-Entry) Procedure in Swine.Circulation. Cardiovascular interventions · 2025Article
- Catheter based left atrial appendage closure in-hospital outcomes in Germany from 2016 to 2020.Clinical research in cardiology : official journal of the German Cardiac Society · 2024Article
- Innovations in ventricular tachycardia ablation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2023Review
- Epicardial access facilitated by carbon dioxide insufflation via intentional coronary vein exit: step-by-step description of the technique and review of the literature.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2023Review
- Advanced ventricular arrhythmia ablation: step-by-step problem-solving.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2023Article
- Epicardial access facilitated by carbon dioxide insufflation for redo ventricular tachycardia ablation in a patient with arrhythmogenic right ventricular dysplasia and dense adhesions.HeartRhythm case reports · 2021Article
- Transcatheter Tricuspid Valve Interventions: An Emerging Field.Current cardiology reports · 2019Review
- A Minimally Invasive, Translational Method to Deliver Hydrogels to the Heart Through the Pericardial Space.JACC. Basic to translational science · 2017Article
- Transcatheter Myocardial Needle Chemoablation During Real-Time Magnetic Resonance Imaging: A New Approach to Ablation Therapy for Rhythm Disorders.Circulation. Arrhythmia and electrophysiology · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
objectivesThe purpose of this study was to test whether a microcatheter can safely be advanced across the right atrial appendage to access the pericardium and then withdrawn despite subsequent high-intensity anticoagulation. We also tested whether transatrial pericardial insufflation of carbon dioxide (CO
backgroundSubxiphoid needle access to the empty pericardium, required for left atrial suture ligation and epicardial ablation for rhythm disorders, risks myocardial or coronary laceration.
methodsA catheter from the femoral vein engaged the right atrial appendage for angiographic confirmation of position. Through that catheter, the back end of a 0.014- or 0.018-inch guidewire crossed the right atrial wall to enter the pericardium and delivered a 2.4-F microcatheter. CO
resultsRight atrial exit succeeded in 11 subjects (85%) and failed uneventfully in 2 subjects. CO
conclusionsWe report the first human intentional transatrial exit procedure. Transatrial microcatheter access to the pericardium can be achieved safely. Pericardial insufflation with CO
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.