Evidence map›Paper›PMID 26617972›Full record

ArticleACS medicinal chemistry letters2015

Phosphonate Pendant Armed Propylene Cross-Bridged Cyclam: Synthesis and Evaluation as a Chelator for Cu-64.

Nikunj Bhatt, Nisarg Soni, Yeong Su Ha, Woonghee Lee, Darpan N Pandya, Swarbhanu Sarkar, Jung Young Kim, Hochun Lee, Sun Hee Kim, Gwang Il An and 1 more

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In one paragraph

Article in ACS medicinal chemistry letters, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 15 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Nikunj BhattDepartment of Molecular Medicine, BK21 Plus KNU Biomedical Convergence Program, Kyungpook National University , Daegu 700-422, South Korea.
Nisarg SoniDepartment of Molecular Medicine, BK21 Plus KNU Biomedical Convergence Program, Kyungpook National University , Daegu 700-422, South Korea.
Yeong Su HaDepartment of Molecular Medicine, BK21 Plus KNU Biomedical Convergence Program, Kyungpook National University , Daegu 700-422, South Korea.
Woonghee LeeDepartment of Molecular Medicine, BK21 Plus KNU Biomedical Convergence Program, Kyungpook National University , Daegu 700-422, South Korea.
Darpan N PandyaDepartment of Molecular Medicine, BK21 Plus KNU Biomedical Convergence Program, Kyungpook National University , Daegu 700-422, South Korea.
Swarbhanu SarkarDepartment of Molecular Medicine, BK21 Plus KNU Biomedical Convergence Program, Kyungpook National University , Daegu 700-422, South Korea.
Jung Young KimMolecular Imaging Research Center, Korea Institute of Radiological and Medical Sciences , Seoul 139-706, South Korea.
Hochun LeeDepartment of Energy Systems Engineering, Daegu Gyeongbuk Institute of Science & Technology , Daegu 711-873, South Korea.
Sun Hee KimWestern Seoul Center, Korea Basic Science Institute , Seoul 120-140, Korea.
Gwang Il AnMolecular Imaging Research Center, Korea Institute of Radiological and Medical Sciences , Seoul 139-706, South Korea.
Jeongsoo YooDepartment of Molecular Medicine, BK21 Plus KNU Biomedical Convergence Program, Kyungpook National University , Daegu 700-422, South Korea.
Kyungpook National University · KRKorea Institute of Radiological and Medical Sciences · KRDaegu Gyeongbuk Institute of Science and Technology · KRKorea Basic Science Institute · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A propylene cross-bridged macrocyclic chelator with two phosphonate pendant arms (PCB-TE2P) was synthesized from cyclam. Various properties of the synthesized chelator, including Cu-complexation, Cu-complex stability, (64)Cu-radiolabeling, and in vivo behavior, were studied and compared with those of a previously reported propylene cross-bridged chelator (PCB-TE2A).

Indexed as

Bifunctional chelatorphosphonate pendant armspropylene cross bridgeradiopharmaceuticals

Identifiers

PMID26617972
PMCPMC4645244
OpenAlexW2275823949

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.