Evidence map›Paper›PMID 26617884›Full record

ArticleInternational journal of clinical and experimental pathology2015

Radiological score for hemorrhage in the patients with portal hypertension.

Wei Ge, Yi Wang, Ya-Juan Cao, Min Xie, Yi-Tao Ding, Ming Zhang, De-Cai Yu

Abstract read
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Article in International journal of clinical and experimental pathology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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3 · Its place in the literature

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2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Wei GeDepartment of General Surgery, The Affiliated Drum Tower Hospital, Medical School of Nanjing University Nanjing 210008, Jiangsu Province, P. R. China.
Yi WangDepartment of Digestive System, The Affiliated Drum Tower Hospital, Medical School of Nanjing University Nanjing 210008, Jiangsu Province, P. R. China.
Ya-Juan CaoDepartment of General Surgery, The Affiliated Drum Tower Hospital, Medical School of Nanjing University Nanjing 210008, Jiangsu Province, P. R. China.
Min XieDepartment of General Surgery, The Affiliated Drum Tower Hospital, Medical School of Nanjing University Nanjing 210008, Jiangsu Province, P. R. China.
Yi-Tao DingDepartment of General Surgery, The Affiliated Drum Tower Hospital, Medical School of Nanjing University Nanjing 210008, Jiangsu Province, P. R. China.
Ming ZhangDepartment of Digestive System, The Affiliated Drum Tower Hospital, Medical School of Nanjing University Nanjing 210008, Jiangsu Province, P. R. China.
De-Cai YuDepartment of General Surgery, The Affiliated Drum Tower Hospital, Medical School of Nanjing University Nanjing 210008, Jiangsu Province, P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

goalTo analyze the risk factors from radiological indices for hemorrhage in the patients with portal hypertension and weight risk factors.

methodWe retrospectively analyzed all cases of portal hypertension with hepatitis B from June 2008 to June 2014 in Nanjing Drum Tower hospital. Patients with hepatocellular carcinoma, portal vein thrombosis, or portal hypertension with other causes, such as autoimmune hepatitis, pancreatitis, or hematological diseases were excluded.

resultsNinety-eight patients were recruited and divided into hemorrhage and non-hemorrhage groups. There were no statistical differences in clinical indexes such as age, prothrombin time, serum albumin, serum creatinine, serum sodium, hemameba, and blood platelet count. However, the differences were statistically significant in total bilirubin, hemoglobin, and liver function with the p values of 0.023, 0.000, and 0.039 respectively. For radiological indices, hemorrhage was correlated with diameter of inferior mesenteric vein (P=0.0528), posterior gastric vein (P=0.0283), and esophageal varices scores (P=0.0221). Logistic procedure was used to construct the model with stepwise selection and finally inferior mesenteric vein, posterior gastric vein, esophageal varices, and short gastric vein were enrolled into the model. These veins were scored according to the diameters and the rates of hemorrhage were increased with the score. We then validated the model with 26 patents from July 2014 to December 2014. The AUC value was 0.8849 in ROC curves for this radiological model.

conclusionsA risk model was constructed including inferior mesenteric vein, esophageal varices, posterior gastric vein, and short gastric vein. This radiological scoring model may be a valuable indicator for hemorrhage of portal hypertension.

Indexed as

AdultAgedCarcinoma, HepatocellularEsophageal and Gastric VaricesFemaleHemorrhageHepatitis BHumansHypertension, PortalLiver NeoplasmsMagnetic Resonance ImagingMaleMesenteric VeinsMiddle AgedPortal VeinRetrospective StudieshemorrhagePortal hypertensionradiologicalrisk assessmentrisk factors

Identifiers

PMID26617884
PMCPMC4637700

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.