Evidence map›Paper›PMID 26617675›Full record

ArticleJournal of foot and ankle research2015

Cavovarus deformity in Charcot-Marie-Tooth disease: is there a hindfoot equinus deformity that needs treatment?

Nicholas A Beckmann, Sebastian I Wolf, Daniel Heitzmann, Annika Wallroth, Sebastian Müller, Thomas Dreher

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Article in Journal of foot and ankle research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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3 · Its place in the literature

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2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Nicholas A BeckmannClinic for Orthopaedics and Trauma Surgery, Heidelberg University Hospital, Schlierbacher Landstrasse 200A, 69118 Heidelberg, Germany.
Sebastian I WolfHeidelberg Motion Lab, Clinic for Orthopaedics and Trauma Surgery, Heidelberg University Hospital, Schlierbacher Landstrasse 200A, 69118 Heidelberg, Germany.
Daniel HeitzmannHeidelberg Motion Lab, Clinic for Orthopaedics and Trauma Surgery, Heidelberg University Hospital, Schlierbacher Landstrasse 200A, 69118 Heidelberg, Germany.
Annika WallrothClinic for Orthopaedics and Trauma Surgery, Heidelberg University Hospital, Schlierbacher Landstrasse 200A, 69118 Heidelberg, Germany.
Sebastian MüllerClinic for Orthopaedics and Trauma Surgery, Heidelberg University Hospital, Schlierbacher Landstrasse 200A, 69118 Heidelberg, Germany.
Thomas DreherClinic for Orthopaedics and Trauma Surgery, Heidelberg University Hospital, Schlierbacher Landstrasse 200A, 69118 Heidelberg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCharcot-Marie-Tooth disease (CMT), one of the most common hereditary neurologic disorders, often results in debilitating cavovarus foot deformities. The deformities are still not fully understood, and the treatment recommendations are consequently heterogeneous, often including calf muscle or Achilles tendon lengthening.

methodsWe examined 40 patients (80 feet) with CMT and bilateral cavovarus deformities (19 men and 21 women, mean age 33.6 ± 14.6 years) and the feet of a healthy control population of 13 individuals (7 men and 6 women, mean age 43.9 ± 10.8 years). In all cases 3D instrumented gait analysis results with both conventional Plug-in-Gait analysis and the Heidelberg Foot Measurement Method (HFMM) were used to determine the sagittal plane kinematics, dorsi-plantar flexion (DPF), tibio-talar dorsiflexion (TTDF), and medial arch angle (MAA), and the results of patients and the control group were compared using the 2 methods. Decreased and increased dorsiflexion using TTDF was defined as 1 standard deviation below or above the mean of the control. Comparisons were done using descriptive statistics, the Pearson correlation coefficient and ANOVA.

resultsThe TTDF was found to be decreased in 18 of the 80 feet examined (22.5 %), normal in 31 feet (38.75 %), and increased in 31 feet (38.75 %). The Pearson coefficient showed a positive correlation with R = 0.765, p < 0.001 between decreased TTDF values found by HFMM and decreased DPF values found with conventional Plug-in-Gait analysis, but a very weak correlation in patients with normal TTDF (R = -0.118) and increased TTDF (R = 0.078). Also, in patients with decreased TTDF values, there was a weak to moderate correlation with the MAA (R = 0.335), but no correlation between the MAA and DPF (R = 0.023).

conclusionsThe HFMM, unlike the conventional Plug-in-Gait analysis, distinguishes between the segments of the foot in foot deformities and facilitates evaluation of the hindfoot equinus component in patients with CMT and cavovarus deformity. Although there is a significant correlation between decreased TTDF with HFMM and decreased DPF with conventional Plug-in-Gait analysis, this correlation was not seen in patients with normal or increased TTDF values. Conventional Plug-in-Gait analysis alone does not indicate if an increased plantar flexion deformity is the result of either a cavus deformity or hindfoot equinus deformity, which limits its usefulness in assisting in treatment decision making.

Identifiers

PMID26617675
PMCPMC4661993

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.