ReviewFrontiers in psychiatry2015
A New Perspective on Delusional States - Evidence for Claustrum Involvement.
Review in Frontiers in psychiatry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.
- Human lesions and animal studies link the claustrum to perception, salience, sleep and pain.Brain : a journal of neurology · 2022Pooled it
- Article
- A Contrast-Agnostic Method for Ultra-High Resolution Claustrum Segmentation.Human brain mapping · 2025Article
- Single neurons and networks in the mouse claustrum integrate input from widespread cortical sources.eLife · 2025Article
- The Role of the Claustrum in Parkinson's Disease and Vascular Parkinsonism: A Matter of Network?Life (Basel, Switzerland) · 2025Review
- The functional connectivity of the human claustrum, according to the Human Connectome Project database.PloS one · 2024Article
- Proteomic Profiling Reveals Specific Molecular Hallmarks of the Pig Claustrum.Molecular neurobiology · 2023Article
- Origin and development of the claustrum in rhesus macaque.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- A Unique "Reversed" Migration of Neurons in the Developing Claustrum.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Models of psychedelic drug action: modulation of cortical-subcortical circuits.Brain : a journal of neurology · 2022Article
- The mystery of claustral neural circuits and recent updates on its role in neurodegenerative pathology.Behavioral and brain functions : BBF · 2021Review
- Changing the Cortical Conductor's Tempo: Neuromodulation of the Claustrum.Frontiers in neural circuits · 2021Review
- The Mouse Claustrum Is Required for Optimal Behavioral Performance Under High Cognitive Demand.Biological psychiatry · 2020Article
- The Acute Effects of the Atypical Dissociative Hallucinogen Salvinorin A on Functional Connectivity in the Human Brain.Scientific reports · 2020Article
- Cytoarchitecture of the dorsal claustrum of the cat: a quantitative Golgi study.Journal of molecular histology · 2019Article
- High Sensitivity Mapping of Cortical Dopamine D2 Receptor Expressing Neurons.Cerebral cortex (New York, N.Y. : 1991) · 2019Article
- Internal Subdivisions of the Marmoset Claustrum Complex: Identification by Myeloarchitectural Features and High Field Strength Imaging.Frontiers in neuroanatomy · 2019Article
- A Role for the Claustrum in Salience Processing?Frontiers in neuroanatomy · 2019Article
- The Claustrum in Relation to Seizures and Electrical Stimulation.Frontiers in neuroanatomy · 2019Review
- Claustrum circuit components for top-down input processing and cortical broadcast.Brain structure & function · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Delusions are a hallmark positive symptom of schizophrenia, although they are also associated with a wide variety of other psychiatric and neurological disorders. The heterogeneity of clinical presentation and underlying disease, along with a lack of experimental animal models, make delusions exceptionally difficult to study in isolation, either in schizophrenia or other diseases. To date, no detailed studies have focused specifically on the neural mechanisms of delusion, although some studies have reported characteristic activation of specific brain areas or networks associated with them. Here, we present a novel hypothesis and extant supporting evidence implicating the claustrum, a relatively poorly understood forebrain nucleus, as a potential common center for delusional states.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.