ArticleEuropean heart journal2016
One-year outcomes and predictors of mortality after MitraClip therapy in contemporary clinical practice: results from the German transcatheter mitral valve interventions registry.
Article in European heart journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 148 papers, 6 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
148 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Transcatheter management of residual mitral regurgitation after transcatheter edge-to-edge repair: a systematic review.Cardiovascular intervention and therapeutics · 2025Pooled it
- Comparative analysis of postoperative outcomes following surgical and transcatheter edge-to-edge mitral valve repair for secondary mitral regurgitation: a meta-analysis & systematic review.Frontiers in surgery · 2025Pooled it
- Mitral valve surgery after a failed MitraClip procedure.Interactive cardiovascular and thoracic surgery · 2021Pooled it
- Pooled it
- Early Experience With Transcatheter Mitral Valve Replacement: A Systematic Review.Journal of the American Heart Association · 2019Pooled it
- Functional status and quality of life after transcatheter mitral valve repair: a prospective cohort study and systematic review.Clinical research in cardiology : official journal of the German Cardiac Society · 2017Pooled it
- Safety and efficacy of the DragonFly system for transcatheter valve repair of degenerative mitral regurgitation: one-year results of the DRAGONFLY-DMR trial.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2024Trial
- Delayed hospitalisation for heart failure after transcatheter repair or medical treatment for secondary mitral regurgitation: a landmark analysis of the MITRA-FR trial.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2022Trial
- Transcatheter reshaping of the mitral annulus in patients with functional mitral regurgitation: one-year outcomes of the MAVERIC trial.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2021Trial
- Novel Transcatheter Edge-to-Edge Repair System for Degenerative Mitral Regurgitation: 1-Year Outcomes.JACC. Asia · 2026Article
- Preprocedural New York Heart Association Class IV Independently Predicts Mortality After Effective Edge-To-Edge Repair for Primary Mitral Regurgitation.Structural heart : the journal of the Heart Team · 2026Article
- Prognostic value of preprocedural pulmonary artery to ascending aorta ratio on non-contrast computed tomography in patients undergoing mitral transcatheter edge-to-edge repair.Heart and vessels · 2026Article
- Multicenter Evaluation of an Edge-to-Edge Repair System in High-Risk Patients With Degenerative Mitral Regurgitation.Structural heart : the journal of the Heart Team · 2026Article
- Impact of Transcatheter Mitral and Tricuspid Valve Repair on Hepatic Function and Outcomes in Patients with Cirrhosis or Advanced Liver Disease-A Personalized Approach.Journal of clinical medicine · 2026Review
- Renal resistive index for risk stratification and functional evaluation after transcatheter mitral valve repair: the ReRISE study.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
- Surgical repair for a single leaflet device attachment due to a gripper failure from the MitraClip main frame: a case report.European heart journal. Case reports · 2025Article
- Beyond multivalvular disease: imaging-guided diagnosis and management of combined functional mitral and tricuspid regurgitation.European heart journal. Imaging methods and practice · 2025Article
- Electrosurgical Laceration and Stabilization of Clip Followed by Transapical Mitral Valve Replacement after Failed Transcatheter Edge-to-Edge Mitral Valve Repair: A Promising Alternative to Surgery.Interdisciplinary cardiovascular and thoracic surgery · 2025Article
- Impact of heart failure severity on the mortality benefit of mitral transcatheter edge-to-edge valve repair.Clinical research in cardiology : official journal of the German Cardiac Society · 2025Article
- Emergent Cardiac Surgery After Transcatheter Structural Heart Procedures: Narrative Review.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025Review
88 more citing papers are in PubMed but not listed here.
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsThe transcatheter mitral valve interventions (TRAMI) registry was established in order to assess safety and efficacy of catheter-based mitral valve interventional techniques in Germany, and prospectively enrolled 828 MitraClip patients (median age 76 years, median log. EuroSCORE I 20.0%) between August 2010 and July 2013. We present the 1-year outcome in this MitraClip cohort-which is the largest published to date. METHODS AND
resultsSeven forty-nine patients (90.5%) were available for 1-year follow-up and included in the following analyses. Mortality, major adverse cardiovascular event rates, and New York Heart Association (NYHA) classes were recorded. Predictors of 1-year mortality were identified by multivariate analysis using a Cox regression model with stepwise forward selection. The 1-year mortality was 20.3%. At 1 year, 63.3% of TRAMI patients pertained to NYHA functional classes I or II (compared with 11.0% at baseline), and self-rated health status (on EuroQuol visual analogue scale) also improved significantly by 10 points. Importantly, a significant proportion of patients regained the complete independence in self-care after MitraClip implantation (independence in 74.0 vs. 58.6% at baseline, P = 0.005). Predictors of 1-year mortality were NYHA class IV (hazard ratio, HR 1.62, P = 0.02), anaemia (HR 2.44, P = 0.02), previous aortic valve intervention (HR 2.12, P = 0.002), serum creatinine ≥1.5 mg/dL (HR 1.77, P = 0.002), peripheral artery disease (HR 2.12, P = 0.0003), left ventricular ejection fraction <30% (HR 1.58, P = 0.01), severe tricuspid regurgitation (HR 1.84, P = 0.003), and procedural failure (defined as operator-reported failure, conversion to surgery, failure of clip placement, or residual post-procedural severe mitral regurgitation) (HR 4.36, P < 0.0001).
conclusionsTreatment of significant MR with MitraClip resulted in significant clinical improvements in a high proportion of TRAMI patients after 12 months. In the TRAMI cohort, the failure of procedural success exhibited the highest hazard ratio concerning the prediction of 1-year mortality.
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