ArticleProceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine2015
Effect of calcium/sodium ion exchange on the osmotic properties and structure of polyelectrolyte gels.
Article in Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 21 citations in OpenAlex.
- Hydrogel composite mimics biological tissues.Soft matter · 2022Article
- Dynamic model of monovalent-divalent cation exchange in polyelectrolyte gels.Physical review materials · 2022Article
- Ion-Induced Volume Transition in Gels and Its Role in Biology.Gels (Basel, Switzerland) · 2021Review
- Experimental Evidence for Universal Behavior of Ion-Induced Volume Phase Transition in Sodium Polyacrylate Gels.The journal of physical chemistry letters · 2019Article
- Decisive test of the ideal behavior of tetra-PEG gels.The Journal of chemical physics · 2017Article
- Article
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
We discuss the main findings of a long-term research program exploring the consequences of sodium/calcium ion exchange on the macroscopic osmotic and elastic properties, and the microscopic structure of representative synthetic polyelectrolyte (sodium polyacrylate, (polyacrylic acid)) and biopolymer gels (DNA). A common feature of these gels is that above a threshold calcium ion concentration, they exhibit a reversible volume phase transition. At the macroscopic level, the concentration dependence of the osmotic pressure shows that calcium ions influence primarily the third-order interaction term in the Flory-Huggins model of polymer solutions. Mechanical tests reveal that the elastic modulus is practically unaffected by the presence of calcium ions, indicating that ion bridging does not create permanent cross-links. At the microscopic level, small-angle neutron scattering shows that polyacrylic acid and DNA gels exhibit qualitatively similar structural features in spite of important differences (e.g. chain flexibility and chemical composition) between the two polymers. The main effect of calcium ions is that the neutron scattering intensity increases due to the decrease in the osmotic modulus. At the level of the counterion cloud around dissolved macroions, anomalous small-angle X-ray scattering measurements made on DNA indicate that divalent ions form a cylindrical sheath enveloping the chain, but they are not localized. Small-angle neutron scattering and small-angle X-ray scattering provide complementary information on the structure and interactions in polymer solutions and gels.
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