ArticleAlcoholism, clinical and experimental research2015
Immediate and Complex Cardiovascular Adaptation to an Acute Alcohol Dose.
Article in Alcoholism, clinical and experimental research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effect of alcohol on blood pressure.The Cochrane database of systematic reviews · 2020Pooled it
- Effects of alcohol on sleep and nocturnal heart rate: Relationships to intoxication and morning-after effects.Alcoholism, clinical and experimental research · 2022Trial
- Effects of short-term exposure to moderate amounts of alcohol on brain volume.Neuropsychopharmacology reports · 2025Article
- A Survey on Blood Pressure Measurement Technologies: Addressing Potential Sources of Bias.Sensors (Basel, Switzerland) · 2024Review
- The Process of Heart Rate Variability, Resonance at 0.1 hz, and the Three Baroreflex Loops: A Tribute to Evgeny Vaschillo.Applied psychophysiology and biofeedback · 2022Article
- Heart Rate Variability Biofeedback for Substance Use Disorder: Health Policy Implications.Policy insights from the behavioral and brain sciences · 2022Article
- Closing the brain-heart loop: Towards more holistic models of addiction and addiction recovery.Addiction biology · 2022Review
- Effects of acute alcohol consumption on neuronal activity and cerebral vasomotor response.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022Article
- Effects of cocaine and/or heroin use on resting cardiovascular function.International journal of cardiology. Cardiovascular risk and prevention · 2021Article
- SUBSTANCE USE AND ADDICTION AFFECT MORE THAN THE BRAIN: THE PROMISE OF NEUROCARDIAC INTERVENTIONS.Current addiction reports · 2021Article
- Mean Versus Variability: Disentangling Stress Effects on Alcohol Lapses Among Individuals in the First Year of Alcohol Use Disorder Recovery.Journal of studies on alcohol and drugs · 2021Article
- 3D bioprinting of cardiac tissue: current challenges and perspectives.Journal of materials science. Materials in medicine · 2021Review
- Article
- Female drinkers are more sensitive than male drinkers to alcohol-induced heart rate increase.Experimental and clinical psychopharmacology · 2020Article
- Elevated resting heart rate is associated with several cardiovascular disease risk factors in urban-dwelling black South Africans.Scientific reports · 2020Article
- Getting to the Heart of Low Sensitivity to Alcohol: Context Moderates Low Cardiovascular Response to Alcohol in Persons With a Family History of Alcohol Use Disorder.Alcoholism, clinical and experimental research · 2020Article
- Dose of Alcohol From Beer Required for Acute Reduction in Arterial Stiffness.Frontiers in physiology · 2020Article
- Theoretical implications and clinical support for heart rate variability biofeedback for substance use disorders.Current opinion in psychology · 2019Review
- Improvement in women's cardiovascular functioning during cognitive-behavioral therapy for alcohol use disorder.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2019Observational
- Early signs of cardiovascular dysregulation in young adult binge drinkers.Psychophysiology · 2018Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundThe detrimental effects of chronic heavy alcohol use on the cardiovascular system are well established and broadly appreciated. Integrated cardiovascular response to an acute dose of alcohol has been less studied. This study examined the early effects of an acute dose of alcohol on the cardiovascular system, with particular emphasis on system variability and sensitivity. The goal was to begin to understand how acute alcohol disrupts dynamic cardiovascular regulatory processes prior to the development of cardiovascular disease.
methodsHealthy participants (N = 72, age 21 to 29) were randomly assigned to an alcohol, placebo, or no-alcohol control beverage condition. Beat-to-beat heart rate (HR) and blood pressure (BP) were assessed during a low-demand cognitive task prior to and following beverage consumption. Between-group differences in neurocardiac response to an alcohol challenge (blood alcohol concentration ~ 0.06 mg/dl) were tested.
resultsThe alcohol beverage group showed higher average HR, lower average stroke volume, lower HR variability and BP variability, and increased vascular tone baroreflex sensitivity after alcohol consumption. No changes were observed in the placebo group, but the control group showed slightly elevated average HR and BP after beverage consumption, possibly due to juice content. At the level of the individual, an active alcohol dose appeared to disrupt the typically tight coupling between cardiovascular processes.
conclusionsA dose of alcohol quickly invoked multiple cardiovascular responses, possibly as an adaptive reaction to the acute pharmacological challenge. Future studies should assess how exposure to alcohol acutely disrupts or dissociates typically integrated neurocardiac functions.
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