Evidence map›Paper›PMID 26614304›Full record

SynthesisTechniques in coloproctology2016

Systematic review of pre-operative exercise in colorectal cancer patients.

C Boereboom, B Doleman, J N Lund, J P Williams

3 registry-linked trialsOpen access · greenAbstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Techniques in coloproctology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 38 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 6 pooled it
2.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03096951 nacompletednot on this mapstarted 2017, after this paper: background citation

Prehabilitation Before Surgery in Colorectal Cancer With Improved Fast Track Rehabilitation : Part 1

TypeinterventionalSponsorCliniques universitaires Saint-Luc- Université Catholique de LouvainRan2017 to 2019Enrolled28ConditionsColon CancerArmsPrehabilitation, Rehabilitation
NCT03097224 naunknown statusnot on this mapstarted 2017, after this paper: background citation

Prehabilitation Before Surgery in Colorectal Cancer With Improved Fast Track Rehabilitation : Part 2

TypeinterventionalSponsorCliniques universitaires Saint-Luc- Université Catholique de LouvainRan2017 to 2020Enrolled40ConditionsColon Cancer, FragilityArmsPrehabilitation
NCT03423056 naunknown statusnot on this mapstarted 2017, after this paper: background citation

Efficacy and Safety of a Preoperative Aerobic Exercise Program in Patients With Gastrointestinal Cancer. A Phase II Clinical Trial

TypeinterventionalSponsorInstituto Nacional de Cancerologia, ColumbiaRan2017 to 2019Enrolled40ConditionsStomach Neoplasms, Colonic Neoplasms, Rectal Neoplasms, Liver NeoplasmArmsPreoperative exercise program
3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 6 syntheses or guidelines pooled it, 99 citations in OpenAlex.

  1. Pooled it
  2. Effect of home-based exercise prehabilitation on postoperative outcomes in colorectal cancer surgery: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Trial
  8. Trial
  9. Review
  10. Article
  11. Review
  12. Nutritional intervention during a teleprehabilitation pilot study in high-risk patients with colorectal cancer: adherence, motivators, and barriers.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Ovarian cancer in the older patient: where are we now? What to do next?Therapeutic advances in medical oncology · 2023
    Review
  18. Advances in the management of peritoneal malignancies.Nature reviews. Clinical oncology · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

C BoereboomUniversity of Nottingham, Royal Derby Hospital, Derby, UK.
B DolemanUniversity of Nottingham, Royal Derby Hospital, Derby, UK. dr.doleman@gmail.com.
J N LundUniversity of Nottingham, Royal Derby Hospital, Derby, UK.
J P WilliamsUniversity of Nottingham, Royal Derby Hospital, Derby, UK.
Royal Derby Hospital · GBUniversity of Nottingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this systematic review was to evaluate the evidence for exercise interventions prior to surgery for colorectal cancer resection. The evidence for use of exercise to improve physical fitness and surgical outcomes is as yet unknown. A systematic search was performed of MEDLINE, EMBASE, CINAHL, AMED and BNI databases for studies involving pre-operative exercise in colorectal cancer patients. Eight studies were included in the review. There is evidence that pre-operative exercise improves functional fitness, and to a lesser extent objectively measurable cardio-respiratory fitness prior to colorectal cancer resection. There is no clear evidence at present that this improvement in fitness translates into reduced peri-operative risk or improved post-operative outcomes. Current studies are limited by risk of bias. This review highlights the common difficulty in transferring promising results in a research setting, into significant improvements in the clinical arena. Future research should focus on which type of exercise is most likely to maximise patient adherence and improvements in cardio-respiratory fitness. Ultimately, adequately powered, randomised controlled trials are needed to investigate whether pre-operative exercise improves post-operative morbidity and mortality.

Indexed as

ColectomyPhysical FitnessColorectal NeoplasmsExercise TherapyHumansPreoperative CareColorectal cancerExerciseMortalitySystematic review

Identifiers

PMID26614304
OpenAlexW2176214213

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.