Evidence map›Paper›PMID 26614195›Full record

ArticleThe international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease2015

Nosocomial transmission of multidrug-resistant tuberculosis.

V Crudu, M Merker, C Lange, E Noroc, E Romancenco, D Chesov, G Günther, S Niemann

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  5. Article
  6. Genetic Profile of Linezolid-ResistantAntibiotics (Basel, Switzerland) · 2021
    Article
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  13. High genetic diversity amongJournal of clinical tuberculosis and other mycobacterial diseases · 2018
    Article
  14. Article
  15. Article
  16. The impact of mixed infections on the interpretation of molecular epidemiology studies of tuberculosis.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2016
    Article
  17. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

V CruduInstitute of Phthisiopneumology, Chisinau, Republic of Moldova.
M MerkerDivision of Molecular Mycobacteriology and German Center for Infection Research (DZIF) Tuberculosis Unit, Borstel, Germany.
C LangeDZIF Tuberculosis Unit, Research Center Borstel, Borstel, Germany; Department of Medicine, University of Namibia School of Medicine, Windhoek, Namibia; Department of Medicine, Karolinska Institute, Stockholm, Sweden; Department of Pneumology & Allergology, Nicolae Testemitanu State University of Medicine and Pharmacy, Chisinau, Republic of Moldova.
E NorocInstitute of Phthisiopneumology, Chisinau, Republic of Moldova.
E RomancencoInstitute of Phthisiopneumology, Chisinau, Republic of Moldova.
D ChesovDepartment of Pneumology & Allergology, Nicolae Testemitanu State University of Medicine and Pharmacy, Chisinau, Republic of Moldova.
G GüntherDZIF Tuberculosis Unit, Research Center Borstel, Borstel, Germany; Department of Medicine, University of Namibia School of Medicine, Windhoek, Namibia.
S NiemannDivision of Molecular Mycobacteriology and German Center for Infection Research (DZIF) Tuberculosis Unit, Borstel, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nosocomial transmission of multidrug-resistant tuberculosis (MDR-TB) was ascertained by 24-locus mycobacterial interspersed repetitive units-variable number of tandem repeats (MIRU-VNTR) and spoligotyping at four hospitals in the Republic of Moldova, a high MDR-TB burden country. Overall, 5.1% of patients with pan-susceptible TB at baseline were identified with MDR-TB during in-patient treatment. In 75% of cases, the MDR-TB strain was genetically distinct from the non-MDR-TB strain at baseline, suggesting a high rate of nosocomial transmission of MDR-TB. The highest proportion (40.3%) of follow-up MDR-TB isolates was associated with the M. tuberculosis URAL 163-15 strain.

Indexed as

Drug Resistance, Multiple, BacterialAntitubercular AgentsCluster AnalysisCross InfectionGenotypeHumansMinisatellite RepeatsMoldovaMycobacterium tuberculosisTuberculosis, Multidrug-ResistantAntitubercular Agents

Identifiers

PMID26614195

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.