Evidence map›Paper›PMID 26614109›Full record

ReviewUrolithiasis2016

Lowering urinary oxalate excretion to decrease calcium oxalate stone disease.

Ross P Holmes, John Knight, Dean G Assimos

Open access · greenAbstract readReview
In one paragraph

Review in Urolithiasis, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 75 citations in OpenAlex.

  1. Trial
  2. Calcium Citrate Versus Calcium Carbonate in the Management of Chronic Hypoparathyroidism: A Randomized, Double-Blind, Crossover Clinical Trial.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
    Trial
  3. Article
  4. Article
  5. Plant-based diets and urological health.Nature reviews. Urology · 2025
    Review
  6. Article
  7. Article
  8. Rare Case ofInternational medical case reports journal · 2025
    Article
  9. Review
  10. Current Dietary and Medical Prevention of Renal Calcium Oxalate Stones.International journal of general medicine · 2024
    Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Ross P HolmesDepartment of Urology, University of Alabama at Birmingham, Birmingham, AL, USA. rholmes@uab.edu.
John KnightDepartment of Urology, University of Alabama at Birmingham, Birmingham, AL, USA.
Dean G AssimosDepartment of Urology, University of Alabama at Birmingham, Birmingham, AL, USA.
University of Alabama at Birmingham · US

Funding

Oxalobacter formigenes colonization and oxalate excretion in calcium oxalate kidney stone diseaseR01DK087967 · NIDDK · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI KNIGHT, JOHN · 2011 to 2020
$3.5M
Endogenous Oxalate SynthesisR01DK073732 · NIDDK · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HOLMES, ROSS P · 2006 to 2014
$2.4M
Dietary Oxalate and Kidney Stone FormationR01DK062284 · NIDDK · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ASSIMOS, DEAN GEORGE · 2002 to 2010
$2.4M
NIDDK NIH HHS DK62284NIDDK NIH HHS DK73732NIDDK NIH HHS DK87967NIDDK NIH HHS R01 DK062284NIDDK NIH HHS R01 DK073732NIDDK NIH HHS R01 DK087967
6 · The paper itself

Abstract

Dietary modifications should be considered as a first line approach in the treatment of idiopathic calcium oxalate nephrolithiasis. The amounts of oxalate and calcium consumed in the diet are significant factors in the development of the disease due to their impact on urinary oxalate excretion. There are a number of strategies that can be employed to reduce oxalate excretion. The consumption of oxalate-rich foods should be avoided and calcium intake adjusted to 1000-1200 mg/day. To encourage compliance it should be emphasized to patients that they be vigilant with this diet as a deviation in any meal or snack could potentially result in significant stone growth. The evidence underlying these two modifications is outlined and other strategies to reduce urinary oxalate excretion are reviewed.

Indexed as

Calcium, DietaryCalcium OxalateHumansIntestinal AbsorptionKidney CalculiOxalatesOxalobacter formigenesCalcium, DietaryCalcium OxalateOxalates

Identifiers

PMID26614109
PMCPMC5114711
OpenAlexW2287554593

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.