ArticleBMC biology2015
Experimental evolution of recombination and crossover interference in Drosophila caused by directional selection for stress-related traits.
Article in BMC biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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19 citing papers in PubMed.
- Article
- Statistical analysis and simulations that account for simultaneous effects of positive, negative, and no crossover interference in multilocus recombination data.BMC genomics · 2025Article
- Mixed Outcomes in Recombination Rates After Domestication: Revisiting Theory and Data.Molecular ecology · 2025Review
- A high-resolution crossover landscape in Drosophila santomea reveals rapid and concerted evolution of multiple properties of crossing over control.PLoS genetics · 2025Article
- Male-biased recombination at chromosome ends in a songbird revealed by precisely mapping crossover positions.G3 (Bethesda, Md.) · 2024Article
- Variation in fine-scale recombination rate in temperature-evolved Drosophila melanogaster populations in response to selection.G3 (Bethesda, Md.) · 2022Article
- Seasonal changes in recombination characteristics in a natural population of Drosophila melanogaster.Heredity · 2021Article
- Adaptive Divergence of Meiotic Recombination Rate in Ecological Speciation.Genome biology and evolution · 2020Article
- Crossover Interference: Shedding Light on the Evolution of Recombination.Annual review of genetics · 2019Review
- Variation in Recombination Rate Is Shaped by Domestication and Environmental Conditions in Barley.Molecular biology and evolution · 2019Article
- Article
- The Genomic Landscape of Crossover Interference in the Desert TreeFrontiers in genetics · 2019Article
- Role ofGenetics · 2018Article
- Variation in recombination frequency and distribution across eukaryotes: patterns and processes.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017Review
- Building Ultra-High-Density Linkage Maps Based on Efficient Filtering of Trustable Markers.Genetics · 2017Article
- Effect of sex, age and genetics on crossover interference in cattle.Scientific reports · 2016Article
- Evolutionary mysteries in meiosis.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2016Review
- Rapid genomic changes in Drosophila melanogaster adapting to desiccation stress in an experimental evolution system.BMC genomics · 2016Article
- Selection Signatures in Four Lignin Genes from Switchgrass Populations Divergently Selected for In Vitro Dry Matter Digestibility.PloS one · 2016Article
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8 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundPopulation genetics predicts that tight linkage between new and/or pre-existing beneficial and deleterious alleles should decrease the efficiency of natural selection in finite populations. By decoupling beneficial and deleterious alleles and facilitating the combination of beneficial alleles, recombination accelerates the formation of high-fitness genotypes. This may impose indirect selection for increased recombination. Despite the progress in theoretical understanding, interplay between recombination and selection remains a controversial issue in evolutionary biology. Even less satisfactory is the situation with crossover interference, which is a deviation of double-crossover frequency in a pair of adjacent intervals from the product of recombination rates in the two intervals expected on the assumption of crossover independence. Here, we report substantial changes in recombination and interference in three long-term directional selection experiments with Drosophila melanogaster: for desiccation (~50 generations), hypoxia, and hyperoxia tolerance (>200 generations each).
resultsFor all three experiments, we found a high interval-specific increase of recombination frequencies in selection lines (up to 40-50% per interval) compared to the control lines. We also discovered a profound effect of selection on interference as expressed by an increased frequency of double crossovers in selection lines. Our results show that changes in interference are not necessarily coupled with increased recombination.
conclusionsOur results support the theoretical predictions that adaptation to a new environment can promote evolution toward higher recombination. Moreover, this is the first evidence of selection for different recombination-unrelated traits potentially leading, not only to evolution toward increased crossover rates, but also to changes in crossover interference, one of the fundamental features of recombination.
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