ReviewMagnetic resonance imaging clinics of North America2016
MR Imaging Biomarkers in Oncology Clinical Trials.
Abstract readReview
In one paragraph
Review in Magnetic resonance imaging clinics of North America, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Applications of TFrontiers in oncology · 2022Pooled it
- Real-Time Quantitative Assessment of Accuracy and Precision of Blood Volume Derived from DCE-MRI in Individual Patients During a Clinical Trial.Tomography (Ann Arbor, Mich.) · 2019Trial
- Evaluating a Cellular Microstructure Model Within Apoptotic Cell Death via Diffusion Magnetic Resonance and Long Diffusion Times.NMR in biomedicine · 2025Article
- Editorial: Dynamic contrast-enhanced imaging: technology progress and clinical application in oncology.Frontiers in oncology · 2025Article
- Dynamic Contrast Enhanced-MRI and Apparent Diffusion Coefficient Quantitation for Differentiate Hepatocellular Carcinoma from Hepatocellular Adenoma.Asian Pacific journal of cancer prevention : APJCP · 2024Article
- An untrained deep learning method for reconstructing dynamic MR images from accelerated model-based data.Magnetic resonance in medicine · 2023Article
- Direct correlation of MRI with histopathology in pediatric renal tumors through the use of a patient-specific 3-D-printed cutting guide: a feasibility study.Pediatric radiology · 2023Article
- Dynamic contrast-enhanced magnetic resonance imaging for evaluating early response to radiosurgery in patients with vestibular schwannoma.Japanese journal of radiology · 2022Article
- Quantitative diffusion MRI of the abdomen and pelvis.Medical physics · 2022Article
- Early Response to Chemotherapy in Malignant Pleural Mesothelioma Evaluated Using Diffusion-Weighted Magnetic Resonance Imaging: Initial Observations.JTO clinical and research reports · 2021Article
- Quantitative multiparametric MRI predicts response to neoadjuvant therapy in the community setting.Breast cancer research : BCR · 2021Article
- Multimodal Molecular Imaging Detects Early Responses to Immune Checkpoint Blockade.Cancer research · 2021Article
- Medical physics challenges in clinical MR-guided radiotherapy.Radiation oncology (London, England) · 2020Review
- Gastric cancer and imaging biomarkers: Part 1 - a critical review of DW-MRI and CE-MDCT findings.European radiology · 2019Review
- MR Imaging-Histology Correlation by Tailored 3D-Printed Slicer in Oncological Assessment.Contrast media & molecular imaging · 2019Review
- Machine learning improves classification of preclinical models of pancreatic cancer with chemical exchange saturation transfer MRI.Magnetic resonance in medicine · 2019Article
- The effects of intravoxel contrast agent diffusion on the analysis of DCE-MRI data in realistic tissue domains.Magnetic resonance in medicine · 2018Article
- Repeatability, reproducibility, and accuracy of quantitative mri of the breast in the community radiology setting.Journal of magnetic resonance imaging : JMRI · 2018Article
- Quantification of hepatocellular carcinoma heterogeneity with multiparametric magnetic resonance imaging.Scientific reports · 2017Article
- Quantitative magnetic resonance imaging biomarkers in oncological clinical trials: Current techniques and standardization challenges.Chronic diseases and translational medicine · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Richard G AbramsonDepartment of Radiology and Radiological Sciences, Institute of Imaging Science, Vanderbilt University, VUIIS 1161 21st Avenue South, AA 1105 MCN, Nashville, TN 37232-2310, USA.
Lori R ArlinghausDepartment of Radiology and Radiological Sciences, Vanderbilt University, 1161 21st Avenue South, AA 1105 MCN, Nashville, TN 37232-2310, USA.
Adrienne N DulaDepartment of Radiology and Radiological Sciences, Institute of Imaging Science, Vanderbilt University, VUIIS 1161 21st Avenue South, AA 1105 MCN, Nashville, TN 37232-2310, USA.
C Chad QuarlesDepartment of Radiology and Radiological Sciences, Institute of Imaging Science, Vanderbilt University, VUIIS 1161 21st Avenue South, AA 1105 MCN, Nashville, TN 37232-2310, USA; Department of Biomedical Engineering, Institute of Imaging Science, Vanderbilt University, VUIIS 1161 21st Avenue South, AA 1105 MCN, Nashville, TN 37232-2310, USA; Department of Cancer Biology, Institute of Imaging Science, Vanderbilt University, 1161 21st Avenue South, AA 1105 MCN, Nashville, TN 37232-2310, USA.
Ashley M StokesDepartment of Radiology and Radiological Sciences, Institute of Imaging Science, Vanderbilt University, VUIIS 1161 21st Avenue South, AA 1105 MCN, Nashville, TN 37232-2310, USA.
Jared A WeisDepartment of Biomedical Engineering, Vanderbilt University, VUIIS 1161 21st Avenue South, AA 1105 MCN, Nashville, TN 37232-2310, USA.
Jennifer G WhisenantDepartment of Radiology and Radiological Sciences, Institute of Imaging Science, Vanderbilt University, VUIIS 1161 21st Avenue South, AA 1105 MCN, Nashville, TN 37232-2310, USA.
Eduard Y ChekmenevDepartment of Radiology and Radiological Sciences, Institute of Imaging Science, Vanderbilt University, VUIIS 1161 21st Avenue South, AA 1105 MCN, Nashville, TN 37232-2310, USA; Department of Biomedical Engineering, Institute of Imaging Science, Vanderbilt University, VUIIS 1161 21st Avenue South, AA 1105 MCN, Nashville, TN 37232-2310, USA; Department of Biochemistry, Institute of Imaging Science, Vanderbilt University, 1161 21st Avenue South, AA 1105 MCN, Nashville, TN 37232-2310, USA.
Igor ZhukovNational Research Nuclear University MEPhI, Kashirskoye highway, 31, Moscow 115409, Russia.
Jason M WilliamsDepartment of Radiology and Radiological Sciences, Institute of Imaging Science, Vanderbilt University, 1161 21st Avenue South, AA 1105 MCN, Nashville, TN 37232-2310, USA.
Thomas E YankeelovDepartment of Radiology and Radiological Sciences, Institute of Imaging Science, Vanderbilt University, VUIIS 1161 21st Avenue South, AA 1105 MCN, Nashville, TN 37232-2310, USA; Department of Biomedical Engineering, Institute of Imaging Science, Vanderbilt University, VUIIS 1161 21st Avenue South, AA 1105 MCN, Nashville, TN 37232-2310, USA; Department of Cancer Biology, Institute of Imaging Science, Vanderbilt University, 1161 21st Avenue South, AA 1105 MCN, Nashville, TN 37232-2310, USA; Department of Physics, Institute of Imaging Science, Vanderbilt University, VUIIS 1161 21st Avenue South, AA 1105 MCN, Nashville, TN 37232-2310, USA. Electronic address: thomas.yankeelov@vanderbilt.edu.
Funding
Postdoctoral Training in Biomedical MRI and MRST32EB001628 · NIBIB · VANDERBILT UNIVERSITY MEDICAL CENTER · PI John C Gore · 2003 to 2026
$7.0MMultidisciplinary Training in Basic and Translational Imaging of CancerR25CA092043 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MANNING, HENRY CHARLES · 2001 to 2015
$6.6MQuantitative MRI for Predicting Response of Breast Cancer to Neoadjuvant TherapyU01CA142565 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI KARCZMAR, GREGORY S., NANDA, RITA · 2010 to 2019
$4.5MMRI Assessment of Tumor Perfusion, Permeability and CellularityR01CA158079 · NCI · VANDERBILT UNIVERSITY · PI QUARLES, CHRISTOPHER CHAD · 2011 to 2021
$3.5MThe Vanderbilt Institute for Clinical and Translational Research (VICTR) KL2KL2RR024977 · NCRR · VANDERBILT UNIVERSITY · PI BERNARD, GORDON RAPHAEL · 2007 to 2011
$3.0MImage Driven Multi-Scale Modeling to Predict Treatment Response in Breast CancerU01CA174706 · NCI · VANDERBILT UNIVERSITY · PI QUARANTA, VITO, YANKEELOV, THOMAS E · 2013 to 2018
$2.5MPure parahydrogen-enhanced metabolic MRI contrast agents for molecular imagingR21EB020323 · NIBIB · SOUTHERN ILLINOIS UNIVERSITY CARBONDALE · PI CHEKMENEV, EDUARD, GOODSON, BOYD M · 2015 to 2016
$416kPure parahydrogen-enhanced metabolic MRI contrast agents for molecular imagingR21EB018014 · NIBIB · SOUTHERN ILLINOIS UNIVERSITY CARBONDALE · PI CHEKMENEV, EDUARD, GOODSON, BOYD M · 2014 to 2015
$407kNCI NIH HHS R01 CA158079NCI NIH HHS R01CA158079NCI NIH HHS R25 CA092043NCI NIH HHS R25CA092043NCI NIH HHS U01 CA142565NCI NIH HHS U01CA142565NCI NIH HHS U01 CA174706NCI NIH HHS U01CA174706NCRR NIH HHS KL2 RR024977NIBIB NIH HHS 1R21EB018014NIBIB NIH HHS 1R21EB020323NIBIB NIH HHS R21 EB018014NIBIB NIH HHS R21 EB020323NIBIB NIH HHS T32 EB001628
Abstract
The authors discuss eight areas of quantitative MR imaging that are currently used (RECIST, DCE-MR imaging, DSC-MR imaging, diffusion MR imaging) in clinical trials or emerging (CEST, elastography, hyperpolarized MR imaging, multiparameter MR imaging) as promising techniques in diagnosing cancer and assessing or predicting response of cancer to therapy. Illustrative applications of the techniques in the clinical setting are summarized before describing the current limitations of the methods.
Indexed as
Biomarkers, TumorClinical Trials as TopicHumansMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMedical OncologyMolecular ImagingNeoplasmsOutcome Assessment, Health CareBiomarkers, TumorCESTDCE-MR imagingDiffusionDSC-MR imagingElastographyHyperpolarizedMultiparametric
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.