Evidence map›Paper›PMID 26613665›Full record

ArticleTrends in parasitology2016

Glycophorins, Blood Groups, and Protection from Severe Malaria.

Samuel C Wassmer, Jane M Carlton

Abstract readComment
In one paragraph

Article in Trends in parasitology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Blood group antigens and malaria susceptibility.Frontiers in cellular and infection microbiology · 2025
    Review
  2. Review
  3. The Centers for Disease Control and Prevention and State Health Departments should include Blood-Type Variables in their Babesiosis Case Reports.Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis · 2020
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Samuel C WassmerDivision of Parasitology, Department of Microbiology, New York University School of Medicine, New York, NY 10010. Electronic address: Samuel.Wassmer@nyumc.org.
Jane M CarltonCenter for Genomics and Systems Biology, Department of Biology, New York University, New York, NY 10003.
New York University · US

Funding

Using Next-Generation Genomics to Study Antimalarial Drug Resistance in IndiaU19AI089676 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CARLTON, JANE M · 2010 to 2023
$22.6M
Medical Research Council G0600230Medical Research Council G19/9NIAID NIH HHS U19 AI089676
6 · The paper itself

Abstract

In Malaŵi, Malungo alibe odi is a saying that translates as: 'Malaria does not ask permission before coming in'. The recent finding of a new severe malaria resistance locus next to a cluster of glycophorin genes involved in Plasmodium falciparum erythrocyte invasion seems to suggest otherwise: that evolutionary pressure is enabling erythrocytes to lock the door to keep malaria out.

Indexed as

Genome-Wide Association StudyAnimalsFemaleGenetic Predisposition to DiseaseHumansMalaria, FalciparumMaleSelection, Geneticgenome-wide association studyPlasmodium falciparum malaria

Identifiers

PMID26613665
PMCPMC4713327
OpenAlexW2173689614

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.