ReviewTrends in parasitology2016
Coinfection by Ixodes Tick-Borne Pathogens: Ecological, Epidemiological, and Clinical Consequences.
Review in Trends in parasitology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 189 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
189 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Global prevalence of Borrelia burgdorferi and Anaplasma phagocytophilum coinfection in wild and domesticated animals: A systematic review and meta-analysis.Journal of global health · 2024Pooled it
- Tick-Borne Diseases in Sub-Saharan Africa: A Systematic Review of Pathogens, Research Focus, and Implications for Public Health.Pathogens (Basel, Switzerland) · 2024Pooled it
- Global meta-analysis onPathogens and global health · 2022Pooled it
- Are there other undiagnosed tick-borne infections in children being evaluated for Lyme neuroborreliosis?BMC pediatrics · 2026Article
- Coinfection ecology and pathogen emergence in aApplied and environmental microbiology · 2026Article
- Habitat-Specific Patterns of Tick-Borne Pathogens in Urban and Suburban Landscapes.Pathogens (Basel, Switzerland) · 2026Article
- Lyme disease as a rare trigger for autoimmune hemolytic anemia.BMC infectious diseases · 2026Article
- From forest floor to doctor's office: the immunological journey ofFrontiers in immunology · 2026Review
- Patient roadmap and economic burden of chronic tick-borne illness and post-treatment Lyme disease syndrome in Ireland, and public health issues arising.Frontiers in public health · 2026Article
- Molecular detection of tick-borne pathogens in cattle ticks from the Lao People's Democratic Republic.Parasites & vectors · 2025Article
- Coinfection Ecology and Pathogen Emergence in amedRxiv : the preprint server for health sciences · 2025Article
- Molecular and serological evidence of spotted fever group rickettsiae and Borrelia co-infection in Ixodes ricinus and humans in north-eastern Poland.Scientific reports · 2025Article
- Molecular characterization of Rhipicephalus microplus and tick-borne pathogens in cattle in Nepal.Veterinary research communications · 2025Article
- Human babesiosis: The past, present and future.Expert reviews in molecular medicine · 2025Review
- Long-term survival ofMicrobiology spectrum · 2025Article
- European Brown hare (International journal for parasitology. Parasites and wildlife · 2025Article
- Two novel rickettsiae (Candidatus Rickettsia isanensis and Candidatus Rickettsia ranongensis) and co-detections of bacteria and protozoa in Amblyomma ticks of reptiles from Thailand.BMC microbiology · 2025Article
- Temporal Dynamic Interplay of Mouse Proteome during ProtozoanJournal of proteome research · 2025Article
- TICKHUNTER: A Targeted Hybridization-Capture Sequencing Approach for the Detection and Characterization of Tick-borne Pathogens and Blood Meals.bioRxiv : the preprint server for biology · 2025Article
- Cattle Zoonotic and Non-Zoonotic Tick-Borne Pathogens in Europe-A Retrospective Analysis of the Past 15 Years.Animals : an open access journal from MDPI · 2025Review
129 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Ixodes ticks maintain a large and diverse array of human pathogens in the enzootic cycle, including Borrelia burgdorferi and Babesia microti. Despite the poor ecological fitness of B. microti, babesiosis has recently emerged in areas endemic for Lyme disease. Studies in ticks, reservoir hosts, and humans indicate that coinfection with B. burgdorferi and B. microti is common, promotes transmission and emergence of B. microti in the enzootic cycle, and causes greater disease severity and duration in humans. These interdisciplinary studies may serve as a paradigm for the study of other vector-borne coinfections. Identifying ecological drivers of pathogen emergence and host factors that fuel disease severity in coinfected individuals will help guide the design of effective preventative and therapeutic strategies.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.