ArticleeLife2015
Using an achiasmic human visual system to quantify the relationship between the fMRI BOLD signal and neural response.
Article in eLife, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Triple-N dataset: large-scale fMRI-guided dense recordings of nonhuman primate neural responses to natural scenes.Nature neuroscience · 2026Article
- BOLD Contrast Response Characteristics of Aberrant Voxels with Bilateral Visual Population Receptive Fields in Human Albinism.bioRxiv : the preprint server for biology · 2024Article
- Clinical features and imaging characteristics in achiasmia.Brain communications · 2023Article
- A modeling framework for determining modulation of neural-level tuning from non-invasive human fMRI data.Communications biology · 2022Article
- Estimating average single-neuron visual receptive field sizes by fMRI.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Greater brain activity during the resting state and the control of activation during the performance of tasks.Scientific reports · 2019Article
- Bayesian analysis of retinotopic maps.eLife · 2018Article
- Compressive Temporal Summation in Human Visual Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Article
- Learning to see again: biological constraints on cortical plasticity and the implications for sight restoration technologies.Journal of neural engineering · 2017Review
- The effects of orientation and attention during surround suppression of small image features: A 7 Tesla fMRI study.Journal of vision · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Achiasma in humans causes gross mis-wiring of the retinal-fugal projection, resulting in overlapped cortical representations of left and right visual hemifields. We show that in areas V1-V3 this overlap is due to two co-located but non-interacting populations of neurons, each with a receptive field serving only one hemifield. Importantly, the two populations share the same local vascular control, resulting in a unique organization useful for quantifying the relationship between neural and fMRI BOLD responses without direct measurement of neural activity. Specifically, we can non-invasively double local neural responses by stimulating both neuronal populations with identical stimuli presented symmetrically across the vertical meridian to both visual hemifields, versus one population by stimulating in one hemifield. Measurements from a series of such doubling experiments show that the amplitude of BOLD response is proportional to approximately 0.5 power of the underlying neural response. Reanalyzing published data shows that this inferred relationship is general.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.