Evidence map›Paper›PMID 26613345›Full record

ArticleEnvironmental research2016

Association between satellite-based estimates of long-term PM2.5 exposure and coronary artery disease.

Laura A McGuinn, Cavin K Ward-Caviness, Lucas M Neas, Alexandra Schneider, David Diaz-Sanchez, Wayne E Cascio, William E Kraus, Elizabeth Hauser, Elaine Dowdy, Carol Haynes and 3 more

Open access · greenAbstract read
In one paragraph

Article in Environmental research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 4 pooled it
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 4 syntheses or guidelines pooled it, 94 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Characteristics of cohort studies of long-term exposure to PMEnvironmental science and pollution research international · 2019
    Pooled it
  4. Pooled it
  5. Article
  6. Article
  7. The Intersection of Socioeconomic and Environmental Factors in Aging: Insights from a Narrative Review.International journal of environmental research and public health · 2025
    Review
  8. Review
  9. Review
  10. Long-Term Exposure to Ambient PMJournal of the American Heart Association · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Association between satellite-based estimates of long-term PMEnvironmental science and pollution research international · 2022
    Article
  15. Impacts of Environmental Insults on Cardiovascular Aging.Current environmental health reports · 2022
    Review
  16. Article
  17. Article
  18. Association between particulate matter air pollution and heart attacks in San Diego County.Journal of the Air & Waste Management Association (1995) · 2021
    Article
  19. Long-term exposure to PMEnvironmental health : a global access science source · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 3 countries.

Laura A McGuinnDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, United States.
Cavin K Ward-CavinessHelmholtz Zentrum München, German Research Center for Environmental Health, Institute of Epidemiology II, Neuherberg, Germany.
Lucas M NeasUS EPA, RTP, NC, United States.
Alexandra SchneiderHelmholtz Zentrum München, German Research Center for Environmental Health, Institute of Epidemiology II, Neuherberg, Germany.
David Diaz-SanchezUS EPA, RTP, NC, United States.
Wayne E CascioUS EPA, RTP, NC, United States.
William E KrausDuke University School of Medicine, Durham, NC, United States.
Elizabeth HauserDuke University School of Medicine, Durham, NC, United States.
Elaine DowdyDuke University School of Medicine, Durham, NC, United States.
Carol HaynesDuke University School of Medicine, Durham, NC, United States.
Alexandra ChudnovskyDepartment of Environmental Health, Harvard School of Public Health, Boston, MA, United States; Department of Geography and Human Environment, Tel-Aviv University, Israel.
Petros KoutrakisDepartment of Environmental Health, Harvard School of Public Health, Boston, MA, United States.
Robert B DevlinUS EPA, RTP, NC, United States. Electronic address: devlin.robert@epa.gov.
Duke University · USEnvironmental Protection Agency · USHelmholtz Zentrum München · DETel Aviv University · ILUniversity of North Carolina at Chapel Hill · US

Funding

Biostatstics for Research in Environmental HealthT32ES007018 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Stephanie Engel, Rebecca Fry · 1985 to 2026
$31.3M
NIEHS NIH HHS T32 ES007018NIEHS NIH HHS T32ES007018
6 · The paper itself

Abstract

backgroundEpidemiological studies have identified associations between long-term PM2.5 exposure and cardiovascular events, though most have relied on concentrations from central-site air quality monitors.

methodsWe utilized a cohort of 5679 patients who had undergone cardiac catheterization at Duke University between 2002-2009 and resided in North Carolina. We used estimates of daily PM2.5 concentrations for North Carolina during the study period based on satellite derived Aerosol Optical Depth (AOD) measurements and PM2.5 concentrations from ground monitors, which were spatially resolved with a 10×10km resolution, matched to each patient's residential address and averaged for the year prior to catheterization. The Coronary Artery Disease (CAD) index was used to measure severity of CAD; scores >23 represent a hemodynamically significant coronary artery lesion in at least one major coronary vessel. Logistic regression modeled odds of having CAD or an MI with each 1μg/m(3) increase in annual average PM2.5, adjusting for sex, race, smoking status and socioeconomic status.

resultsIn adjusted models, a 1μg/m(3) increase in annual average PM2.5 was associated with an 11.1% relative increase in the odds of significant CAD (95% CI: 4.0-18.6%) and a 14.2% increase in the odds of having a myocardial infarction (MI) within a year prior (95% CI: 3.7-25.8%).

conclusionsSatellite-based estimates of long-term PM2.5 exposure were associated with both coronary artery disease (CAD) and incidence of myocardial infarction (MI) in a cohort of cardiac catheterization patients.

Indexed as

AdultAgedAged, 80 and overCohort StudiesCoronary Artery DiseaseEnvironmental ExposureFemaleHumansIncidenceLogistic ModelsMaleMiddle AgedNorth CarolinaParticle SizeParticulate MatterSatellite CommunicationsParticulate MatterCoronary diseaseEpidemiologyMyocardial infarctionPM(2.5)Spatiotemporal analyses

Identifiers

PMID26613345
PMCPMC4706491
OpenAlexW2200859699

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.