Evidence map›Paper›PMID 26613038›Full record

ArticleClinical kidney journal2015

Nephrology care prior to end-stage renal disease and outcomes among new ESRD patients in the USA.

Brenda W Gillespie, Hal Morgenstern, Elizabeth Hedgeman, Anca Tilea, Natalie Scholz, Tempie Shearon, Nilka Rios Burrows, Vahakn B Shahinian, Jerry Yee, Laura Plantinga and 5 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical kidney journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03832166 (A Prospective, Randomized Two Group Study to Evaluate the Feasibility and Initial Efficacy of a Community-engaged Screening, Identification, and F&V Intervention to Improve F&V Intake and CKD Outcomes in 140 AA Adults), which is not on this map. Cited by 53 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03832166 nacompletednot on this mapstarted 2019, after this paper: background citation

A Prospective, Randomized Two Group Study to Evaluate the Feasibility and Initial Efficacy of a Community-engaged Screening, Identification, and F&V Intervention to Improve F&V Intake and CKD Outcomes in 140 AA Adults

TypeinterventionalSponsorBaylor Research InstituteRan2019 to 2020Enrolled142ConditionsCKD, ESRDArmsFruits and Vegetables, Cooking
3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. A Microsimulation-Based Approach for Mitigating Societal Bias in Chronic Kidney Disease Data.Medical decision making : an international journal of the Society for Medical Decision Making · 2026
    Article
  4. A microsimulation-based framework for mitigating societal bias in primary care data.medRxiv : the preprint server for health sciences · 2025
    Article
  5. Article
  6. Article
  7. Article
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  9. Review
  10. Article
  11. Article
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  15. Article
  16. Farewell from theClinical kidney journal · 2022
    Article
  17. Early steps to kidney transplantation among persons with HIV and end-stage renal disease in ESRD network 6.Transplant infectious disease : an official journal of the Transplantation Society · 2022
    Article
  18. Article
  19. Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Brenda W GillespieKidney Epidemiology and Cost Center , University of Michigan , Ann Arbor, MI , USA ; Department of Biostatistics , University of Michigan , Ann Arbor, MI , USA ; Center for Statistical Consultation and Research, University of Michigan , Ann Arbor, MI , USA.
Hal MorgensternDepartment of Epidemiology , University of Michigan School of Public Health , Ann Arbor, MI , USA ; Department of Environmental Health Sciences , University of Michigan School of Public Health , Ann Arbor, MI , USA ; Department of Urology , University of Michigan Medical School , Ann Arbor, MI , USA.
Elizabeth HedgemanEpidStat Institute , Ann Arbor, MI , USA.
Anca TileaKidney Epidemiology and Cost Center , University of Michigan , Ann Arbor, MI , USA ; Department of Internal Medicine , University of Michigan , Ann Arbor, MI , USA.
Natalie ScholzKidney Epidemiology and Cost Center , University of Michigan , Ann Arbor, MI , USA ; Department of Biostatistics , University of Michigan , Ann Arbor, MI , USA.
Tempie ShearonKidney Epidemiology and Cost Center , University of Michigan , Ann Arbor, MI , USA ; Department of Biostatistics , University of Michigan , Ann Arbor, MI , USA.
Nilka Rios BurrowsDivision of Diabetes Translation , Centers for Disease Control and Prevention , Atlanta, GA , USA.
Vahakn B ShahinianKidney Epidemiology and Cost Center , University of Michigan , Ann Arbor, MI , USA ; Department of Internal Medicine , University of Michigan , Ann Arbor, MI , USA.
Jerry YeeHenry Ford Health System , Detroit, MI , USA.
Laura PlantingaDepartment of Epidemiology , Emory University , Atlanta, GA , USA.
Neil R PoweDepartment of Medicine , San Francisco General Hospital and University of California , San Francisco, CA , USA.
William McClellanDepartment of Epidemiology , Emory University , Atlanta, GA , USA.
Bruce RobinsonArbor Research Collaborative for Health , Ann Arbor, MI , USA.
Desmond E WilliamsDivision of Diabetes Translation , Centers for Disease Control and Prevention , Atlanta, GA , USA.
Rajiv SaranKidney Epidemiology and Cost Center , University of Michigan , Ann Arbor, MI , USA ; Department of Epidemiology , University of Michigan School of Public Health , Ann Arbor, MI , USA ; Department of Internal Medicine , University of Michigan , Ann Arbor, MI , USA.

Funding

COOPERATIVE AGREEMENT WITH THE ASSOCIATION OF AMERICAN MEDICAL COLLEGESU36CD319276 · CD · ASSOCIATION OF AMERICAN MEDICAL COLLEGES · PI GROVER, ATUL · 2000 to 2011
$26.1M
ESTABLISHING A SURVEILLANCE SYSTEM FOR CHRONIC KIDNEY DISEASE-COMPONENT 1U58DP003836 · DP · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SARAN, RAJIV · 2011 to 2014
$1.8M
NCCDPHP CDC HHS U58 DP003836ODCDC CDC HHS U36 CD319276
6 · The paper itself

Abstract

backgroundLonger nephrology care before end-stage renal disease (ESRD) has been linked with better outcomes.

methodsWe investigated whether longer pre-end-stage renal disease (ESRD) nephrology care was associated with lower mortality at both the patient and state levels among 443 761 incident ESRD patients identified in the USA between 2006 and 2010.

resultsOverall, 33% of new ESRD patients had received no prior nephrology care, while 28% had received care for >12 months. At the patient level, predictors of >12 months of nephrology care included having health insurance, white race, younger age, diabetes, hypertension and US region. Longer pre-ESRD nephrology care was associated with lower first-year mortality (adjusted hazard ratio = 0.58 for >12 months versus no care; 95% confidence interval 0.57-0.59), higher albumin and hemoglobin, choice of peritoneal dialysis and native fistula and discussion of transplantation options. Living in a state with a 10% higher proportion of patients receiving >12 months of pre-ESRD care was associated with a 9.3% lower relative mortality rate, standardized for case mix (R (2) = 0.47; P < 0.001).

conclusionsThis study represents the largest cohort of incident ESRD patients to date. Although we did not follow patients before ESRD onset, our findings, both at the individual patient and state levels, reflect the importance of early nephrology care among those with chronic kidney disease.

Indexed as

dialysisglomerular filtration ratekidney transplantationnephrology referralvascular access

Identifiers

PMID26613038
PMCPMC4655805

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.