Evidence map›Paper›PMID 26612500›Full record

ReviewTrends in microbiology2016

Household Transmission of Influenza Virus.

Tim K Tsang, Lincoln L H Lau, Simon Cauchemez, Benjamin J Cowling

Registry-linked trialOpen access · bronzeAbstract readReview
In one paragraph

Review in Trends in microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06161454 (A Feasibility Study of Xofluza Treatment of Influenza in Pediatric Transplant Recipients, Waitlisted Subjects and Household Members After Early Infection Alerting Using Wearable Devices), which is not on this map. Cited by 94 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
94citing papers in PubMed, 7 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06161454 phase4completednot on this mapstarted 2023, after this paper: background citation

A Feasibility Study of Xofluza Treatment of Influenza in Pediatric Transplant Recipients, Waitlisted Subjects and Household Members After Early Infection Alerting Using Wearable Devices

TypeinterventionalSponsorChildren's Hospital of PhiladelphiaRan2023 to 2025Enrolled498ConditionsInfection, Coronavirus, Infections, Influenza, TransplantArmsBaloxavir Marboxil
3 · Its place in the literature

Who cites it

94 citing papers in PubMed, 7 syntheses or guidelines pooled it, 146 citations in OpenAlex.

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  5. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Setting-specific Transmission Rates: A Systematic Review and Meta-analysis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
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34 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Tim K TsangWHO Collaborating Centre for Infectious Disease Epidemiology and Control, School of Public Health, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong Special Administrative Region, China.
Lincoln L H LauDalla Lana School of Public Health, University of Toronto, Toronto, Canada.
Simon CauchemezMathematical Modelling of Infectious Diseases Unit, Institut Pasteur, Paris, France.
Benjamin J CowlingWHO Collaborating Centre for Infectious Disease Epidemiology and Control, School of Public Health, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong Special Administrative Region, China. Electronic address: bcowling@hku.hk.
University of Hong Kong · HKInstitut Pasteur · FRUniversity of Toronto · CA

Funding

Understanding and controlling antibiotic resistanceU54GM088558 · NIGMS · HARVARD SCHOOL OF PUBLIC HEALTH · PI LIPSITCH, MARC · 2009 to 2018
$26.4M
Models for synthesising molecular, clinical and epidemiological data, and translaU01GM110721 · NIGMS · IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE · PI CAUCHEMEZ, SIMON, FERGUSON, NEIL MORRIS · 2014 to 2018
$1.9M
NIGMS NIH HHS 1U01GM110721-01NIGMS NIH HHS U01 GM110721NIGMS NIH HHS U54 GM088558
6 · The paper itself

Abstract

Human influenza viruses cause regular epidemics and occasional pandemics with a substantial public health burden. Household transmission studies have provided valuable information on the dynamics of influenza transmission. We reviewed published studies and found that once one household member is infected with influenza, the risk of infection in a household contact can be up to 38%, and the delay between onset in index and secondary cases is around 3 days. Younger age was associated with higher susceptibility. In the future, household transmission studies will provide information on transmission dynamics, including the correlation of virus shedding and symptoms with transmission, and the correlation of new measures of immunity with protection against infection.

Indexed as

Contact TracingFamily CharacteristicsHumansInfluenza, HumanOrthomyxoviridaecontrolhouseholdsinfluenzapublic healthtransmission

Identifiers

PMID26612500
PMCPMC4733423
OpenAlexW2256712157

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.